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Cirrhosis: Dermatological Features

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Atlas of Dermatological Manifestations of Gastrointestinal Disease

Abstract

Clinical characteristics include:

Liver disease often presents with cutaneous findings: chronic alcoholism, 43 % have cutaneous findings; alcohol cirrhosis, 72 % have spider angioma, palmar erythema, or Dupuytren’s contractures

Jaundice: occurs when serum bilirubin >2.5–3.0 mg/dL; if mild, skin is yellow; if severe, skin is brown

Pruritus of cholestasis: tends to be generalized, worse in hands and feet

Prurigo nodularis: associated especially with cirrhosis due to hepatitis C; firm, pruritic hyperkeratotic nodules 1 mm–2 cm in diameter; usually on the extremities although no part of the body is exempt, often with xerotic/lichenified skin between nodules and excoriations/crusting on the lesions

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References

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Author information

Authors and Affiliations

  1. Yale Department of Internal Medicine, Yale New Haven Hospital, New Haven, CT, USA

    Liam Zakko

  2. Yale Primary Care Clinic, 789 Howard Avenue, New Haven, CT, 06519-1304, USA

    Liam Zakko

  3. Department of Dermatology, University of Connecticut Health Center, 21 South Road, Farmington, CT, 06030, USA

    Justin Finch, Marti J. Rothe & Jane M. Grant-Kels

Authors
  1. Liam Zakko
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  2. Justin Finch
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  3. Marti J. Rothe
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  4. Jane M. Grant-Kels
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Corresponding author

Correspondence to Liam Zakko .

Editor information

Editors and Affiliations

  1. Department of Medicine, Gastroenterology Division,, University of Connecticut Health Center, 263 Farmington Ave., Farmington, 06030, Connecticut, USA

    George Y. Wu

  2. , Department of Medicine, University of Connecticut, 56 Kingswood Road, West Hartford, 06119, Connecticut, USA

    Nathan Selsky

  3. , Univ. of CT Health Ctr, Dermatol. Dept., University of Connecticut, 21 South Road, Farmington, 06032, Connecticut, USA

    Jane M. Grant-Kels

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Zakko, L., Finch, J., Rothe, M.J., Grant-Kels, J.M. (2013). Cirrhosis: Dermatological Features. In: Wu, G., Selsky, N., Grant-Kels, J. (eds) Atlas of Dermatological Manifestations of Gastrointestinal Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6191-3_68

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  • DOI: https://doi.org/10.1007/978-1-4614-6191-3_68

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6190-6

  • Online ISBN: 978-1-4614-6191-3

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