Liver disease often presents with cutaneous findings: chronic alcoholism, 43 % have cutaneous findings; alcohol cirrhosis, 72 % have spider angioma, palmar erythema, or Dupuytren’s contractures
Jaundice: occurs when serum bilirubin >2.5–3.0 mg/dL; if mild, skin is yellow; if severe, skin is brown
Pruritus of cholestasis: tends to be generalized, worse in hands and feet
Prurigo nodularis: associated especially with cirrhosis due to hepatitis C; firm, pruritic hyperkeratotic nodules 1 mm–2 cm in diameter; usually on the extremities although no part of the body is exempt, often with xerotic/lichenified skin between nodules and excoriations/crusting on the lesions
Esophageal Varix Alcoholic Cirrhosis Filter Bile Palmar Fascia Cutaneous Finding
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Hazin R, Abu-Rajab Tamimi TI, Abuzetun JY, Zein NN. Recognizing and treating cutaneous signs of liver disease. Cleveland Clin J Med. 2009;76:599–606.CrossRefGoogle Scholar