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Cirrhosis: Dermatological Features

  • Liam Zakko
  • Justin Finch
  • Marti J. Rothe
  • Jane M. Grant-Kels
Chapter

Abstract

Clinical characteristics include:

Liver disease often presents with cutaneous findings: chronic alcoholism, 43 % have cutaneous findings; alcohol cirrhosis, 72 % have spider angioma, palmar erythema, or Dupuytren’s contractures

Jaundice: occurs when serum bilirubin >2.5–3.0 mg/dL; if mild, skin is yellow; if severe, skin is brown

Pruritus of cholestasis: tends to be generalized, worse in hands and feet

Prurigo nodularis: associated especially with cirrhosis due to hepatitis C; firm, pruritic hyperkeratotic nodules 1 mm–2 cm in diameter; usually on the extremities although no part of the body is exempt, often with xerotic/lichenified skin between nodules and excoriations/crusting on the lesions

Keywords

Esophageal Varix Alcoholic Cirrhosis Filter Bile Palmar Fascia Cutaneous Finding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Lee MR, Shumack S. Prurigo nodularis: a review. Australas J Dermatol. 2005;46:211–20.PubMedCrossRefGoogle Scholar
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    Ruocco V, Psilogenis M, Schiavo AL, Wolf R. Dermatologic manifestations of alcoholic cirrhosis. Clin Dermatol. 1999;17:463–8.PubMedCrossRefGoogle Scholar
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    Serrao R, Zirwas M, English JC. Palmar erythema. Am J Clin Dermatol. 2007;8:347–56.PubMedCrossRefGoogle Scholar
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    Ghosn SH, Kibbi AG. Cutaneous manifestations of liver diseases. Clin Dermatol. 2008;26:274–82.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Liam Zakko
    • 1
    • 2
  • Justin Finch
    • 3
  • Marti J. Rothe
    • 3
  • Jane M. Grant-Kels
    • 3
  1. 1.Yale Department of Internal MedicineYale New Haven HospitalNew HavenUSA
  2. 2.Yale Primary Care ClinicNew HavenUSA
  3. 3.Department of DermatologyUniversity of Connecticut Health CenterFarmingtonUSA

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