Abstract
Clinical signs and features include:
Four clinical varieties:
Classical: painful deep ulcer with a violaceous, undermined border and necrotic, purulent center; can start as papule and progress to ulcer
Pustular: painful, sterile pustule with no ulcerative progression
Bullous: presents as a tense bulla that rapidly progresses to an ulcer
Vegetative: superficial ulcer that progresses to a vegetative/exophytic lesion
Seventy percent of lesions on lower extremity, but can be at any skin location (often peristomal)
Often exhibits pathergy
Among patients with ulcerative colitis, 0.5–20 % develop pyoderma gangrenosum (PG) usually during a flare
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Zakko, L., Finch, J., Rothe, M.J., Grant-Kels, J.M. (2013). Pyoderma Gangrenosum. In: Wu, G., Selsky, N., Grant-Kels, J. (eds) Atlas of Dermatological Manifestations of Gastrointestinal Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6191-3_50
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DOI: https://doi.org/10.1007/978-1-4614-6191-3_50
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