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Behçet’s Syndrome: Dermatological Features

  • Liam Zakko
  • Justin Finch
  • Marti J. Rothe
  • Jane M. Grant-Kels
Chapter

Abstract

Clinical signs and features include:

Hallmark is recurrent aphthous ulcers: three types: minor (<10 mm), major (>10 mm; more painful and more likely to scar), herpetiform

Oral ulcers are usually the earliest manifestation of disease and may be the only symptom for many years

The disease usually first presents during the third decade of life and affects males and females equally

Genital ulcers occur in 57–93 % of patients and subside after weeks and recur in days to months

Ulcers affect the scrotum rather than the glans penis and the labia minora and majora

Clinical signs and features include:

Hallmark is recurrent aphthous ulcers: three types: minor (<10 mm), major (>10 mm; more painful and more likely to scar), herpetiform

Keywords

Stevens Johnson Syndrome Genital Ulcer Erythema Nodosum Leukocytoclastic Vasculitis Labium Minora 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Ekinci NS, Alpsoy E, Karakas AA, et al. IL-17A has an important role in the acute attacks of Behcet’s disease. J Invest Dermatol. 2010;130:2136–8.PubMedCrossRefGoogle Scholar
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    O’Neill TW, Rigby AS, Silman AJ, et al. Validation of the international study group criteria for Behcet’s disease. Br J Rheumatol. 1994;33:115–7.PubMedCrossRefGoogle Scholar
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    Alpsoy E. New evidence-based treatment approach in Behçet’s disease. Patholog Res Int. 2012;2012:11, 871019.Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Liam Zakko
    • 1
  • Justin Finch
    • 2
  • Marti J. Rothe
    • 2
  • Jane M. Grant-Kels
    • 2
  1. 1.Yale Department of Internal MedicineYale New Haven HospitalNew HavenUSA
  2. 2.Department of DermatologyUniversity of Connecticut Health CenterFarmingtonUSA

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