Taurine 8 pp 51-58 | Cite as

Effect of Taurine Feeding on Bone Mineral Density and Bone Markers in Rats

  • Mi-Ja ChoiEmail author
  • Ji-Na Seo
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 776)


The purpose of this study was to investigate the effect of dietary taurine supplementation on bone mineral density (BMD) and bone mineral content (BMC) in rats. Twenty Sprague–Dawley male rats (body weight 200 ± 10 g) were divided into two groups, control and taurine group (2% taurine-supplemented diet). All rats were fed on experimental diet and deionized water and libitum for 6 weeks. Serum alkaline phosphatase (ALP) activity, osteocalcin, PTH, and urinary deoxypyridinoline cross-links value were measured as markers of bone formation and resorption. BMD and BMC were measured using PIXImus (GE Lunar Co., Wisconsin) in spine and femur. The effect of diet on ALP, osteocalcine, and PTH was not significant. There were no significant differences in ALP, osteocalcine, and PTH concentration. Urinary calcium excretion was lower in taurine group than in control group. Femur BMC/weight of taurine group was significantly higher than control group. The results of this study showed the possible role of taurine in bone metabolism in male rats.


Bone Mineral Density Bone Mineral Content Spine Bone Mineral Density Urinary Calcium Excretion Femur Bone Mineral Density 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Alkaline phosphatase






Creatinine excretion


Bone mineral density


Bone mineral content


Food efficiency ratio


Spine bone mineral density


Spine bone mineral content


Femur bone mineral density


Femur bone mineral content


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Food and NutritionKeimyung UniversityDaeguSouth Korea

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