Taurine 8 pp 105-111 | Cite as

Positive Correlation Between Serum Taurine and Adiponectin Levels in High-Fat Diet-Induced Obesity Rats

  • Jeong Soon You
  • Xu Zhao
  • Sung Hoon Kim
  • Kyung Ja ChangEmail author
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 776)


The purpose of this study was to investigate the relationship between serum taurine level and serum adiponectin or leptin levels in high-fat diet-induced obesity rats. Five-week-old male Sprague–Dawley rats were randomly divided into three groups for a period of 8 weeks (normal diet, N group; high-fat diet, HF group; high-fat diet + taurine, HFT group). Taurine was supplemented by dissolving in feed water (3% w/v), and the same amount of distilled water was orally administrated to N and HF groups. In serum, adiponectin level was higher in HFT group compared to HF group. The serum taurine level was negatively correlated with serum total cholesterol (TC) level and positively correlated with serum adiponectin level. These results suggest that dietary taurine supplementation has beneficial effects on total cholesterol and adiponectin levels in high-fat diet-induced obesity rats.


Adiponectin Level Serum Adiponectin Serum Lipid Profile Serum Adiponectin Level Taurine Supplementation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Normal diet


High-fat diet


High-fat diet + taurine


Epididymal fat


Retroperitoneal fat




Total cholesterol


High-density lipoprotein-cholesterol


Body weight



We thank the Dong-A Pharmaceutical Co. which donated taurine.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Jeong Soon You
    • 1
  • Xu Zhao
    • 1
  • Sung Hoon Kim
    • 2
  • Kyung Ja Chang
    • 1
    Email author
  1. 1.Deptartment of Food and NutritionInha UniversityIncheonSouth Korea
  2. 2.Department of ChemistryKonkuk UniversitySeoulSouth Korea

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