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Positive Correlation Between Serum Taurine and Adiponectin Levels in High-Fat Diet-Induced Obesity Rats

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Taurine 8

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 776))

Abstract

The purpose of this study was to investigate the relationship between serum taurine level and serum adiponectin or leptin levels in high-fat diet-induced obesity rats. Five-week-old male Sprague–Dawley rats were randomly divided into three groups for a period of 8 weeks (normal diet, N group; high-fat diet, HF group; high-fat diet + taurine, HFT group). Taurine was supplemented by dissolving in feed water (3% w/v), and the same amount of distilled water was orally administrated to N and HF groups. In serum, adiponectin level was higher in HFT group compared to HF group. The serum taurine level was negatively correlated with serum total cholesterol (TC) level and positively correlated with serum adiponectin level. These results suggest that dietary taurine supplementation has beneficial effects on total cholesterol and adiponectin levels in high-fat diet-induced obesity rats.

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Abbreviations

N:

Normal diet

HF:

High-fat diet

HFT:

High-fat diet + taurine

E-fat:

Epididymal fat

R-fat:

Retroperitoneal fat

TG:

Triglyceride

TC:

Total cholesterol

HDL-C:

High-density lipoprotein-cholesterol

BW:

Body weight

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Acknowledgement

We thank the Dong-A Pharmaceutical Co. which donated taurine.

Author information

Authors and Affiliations

  1. Deptartment of Food and Nutrition, Inha University, Incheon, South Korea

    Jeong Soon You, Xu Zhao & Kyung Ja Chang

  2. Department of Chemistry, Konkuk University, Seoul, South Korea

    Sung Hoon Kim

Authors
  1. Jeong Soon You
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  2. Xu Zhao
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  3. Sung Hoon Kim
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  4. Kyung Ja Chang
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Corresponding author

Correspondence to Kyung Ja Chang .

Editor information

Editors and Affiliations

  1. City University of New York, Center for Developmental Neuroscience, College of Staten Island, 2800 Victory Blvd, Staten Island, 10314, New York, USA

    Abdeslem El Idrissi

  2. City University of New York, Department of Biology, College of Staten Island, Victory Blvd 2800, Staten Island, 10314, New York, USA

    William J. L'Amoreaux

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You, J.S., Zhao, X., Kim, S.H., Chang, K.J. (2013). Positive Correlation Between Serum Taurine and Adiponectin Levels in High-Fat Diet-Induced Obesity Rats. In: El Idrissi, A., L'Amoreaux, W. (eds) Taurine 8. Advances in Experimental Medicine and Biology, vol 776. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6093-0_11

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