Transbronchoscopic Emphysema Treatment with One-Way Zephyr Valves

  • Amarilio Vieira de Macedo-Neto
  • Hugo G. de Oliveira


Few alternatives are available for emphysema treatment. The high mortality associated with volume reduction surgery (LVRS) and lung transplantation has greatly restricted their applicability. As a result, minimally invasive alternatives have been developed using the same rationale underlying LVRS—to decrease or prevent air trapping in lung that is damaged by emphysema with reexpansion of the remaining tissue. This chapter will focus on one of these minimally invasive approaches, namely, transbronchoscopic placement of one-way valves. This technique is safe and reversible, although it is still limited by the absence of a clear understanding regarding the best selection criteria. This gap is due in part to a poorly designed trial, which ended up slowing down the acceptance of this promising technique.


Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease Exacerbation Lung Volume Reduction Surgery Small Airway Disease Emphysema Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Editorial support was provided by Claudia Buchweitz.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Amarilio Vieira de Macedo-Neto
    • 1
  • Hugo G. de Oliveira
    • 2
  1. 1.Department of Thoracic SurgeryHospital de Clinicas de Porto AlegrePorto AlegreBrazil
  2. 2.Emphysema Treatment GroupHospital Moinhos de VentoPorto AlegreBrazil

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