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Role of Mast Cells in Angiogenesis

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Biochemical Basis and Therapeutic Implications of Angiogenesis

Part of the book series: Advances in Biochemistry in Health and Disease ((ABHD,volume 6))

Abstract

Angiogenesis is a process that leads to the development of a new vascular network starting from pre-existing capillaries and venules. Mast cells (MCs) are tissue resident cells which actively participate in the angiogenic scenario, playing an important role in normal angiogenesis, angiogenesis that accompanies inflammation and tumour-associated angiogenesis. This chapter will focus on the specific role of MCs in the different types of angiogenic processes.

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Acknowledgements

This work is supported by European Union Seventh Framework Programme (FPT7/2007-2013) under grant agreement no. 278570 to DR.

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Authors and Affiliations

  1. Department of Experimental and Clinical Medicine, Section of Anatomy, University of Udine Medical School, Udine, Italy

    Enrico Crivellato

  2. Department of Basic Medical Sciences, Neurosciences, and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School, Piazza G. Cesare, 11, Policlinico, 70124, Bari, Italy

    Domenico Ribatti

Authors
  1. Enrico Crivellato
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  2. Domenico Ribatti
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Correspondence to Domenico Ribatti .

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Editors and Affiliations

  1. Div. of Cardiovascular Medicine, UAMS, Little Rock, AR, USA, 4301 W Markham, Little Rock, 72205, Arkansas, USA

    Jawahar L. Mehta

  2. Institute of Cardiovascular Sciences, St. Boniface Hosp. Research, Univ. of Ma, 351 Tache Avenue, Winnipeg, R2H 2A6, Manitoba, Canada

    Naranjan S. Dhalla

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Crivellato, E., Ribatti, D. (2013). Role of Mast Cells in Angiogenesis. In: Mehta, J., Dhalla, N. (eds) Biochemical Basis and Therapeutic Implications of Angiogenesis. Advances in Biochemistry in Health and Disease, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5857-9_7

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