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Diabetes pp 272-287 | Cite as

Oxidative Stress in Diabetes

  • Krisztian Stadler
Part of the Advances in Experimental Medicine and Biology book series (AEMB)

Abstract

Oxidative stress and diabetes, both Type 1 and Type 2 as well as their related conditions have been extensively studied. As diabetes, obesity and metabolic syndrome have reached at epidemic levels, there is a huge need and effort to understand the detailed molecular mechanisms of the possible redox imbalance, underlying the cause of pathology and progression of the disease. These studies provide new insights at cellular and subcellular levels to design effective clinical interventions. This chapter is intended to emphasize the latest knowledge and current evidence on the role of oxidative stress in diabetes as well as to discuss some key questions that are currently under discussion.

Keywords

Oxidative Stress Insulin Resistance Aldose Reductase NLRP3 Inflammasome Spin Trap 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Landes Bioscience and Springer Science+Business Media 2013

Authors and Affiliations

  • Krisztian Stadler
    • 1
  1. 1.Pennington Biomedical Research CenterBaton RougeUSA

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