Biomaterial and Therapeutic Applications

  • Veda EswarappaEmail author
  • Sujata K. Bhatia
Part of the SpringerBriefs in Public Health book series (BRIEFSPUBLIC)


Sepsis, a condition in which the bloodstream is fighting a systemic infection, is a major health concern in both developed and developing countries.


Human Serum Albumin Rice Husk Silk Fibroin Dextran Sodium Sulfate Bioactive Glass 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Abraham C, Cho JH (2009) Inflammatory bowel disease. N Eng J of Med 361:2066–2078Google Scholar
  2. Akao Y et al (2004) A highly bioactive lignophenol derivative from bamboo lignin exhibits a potent activity to suppress apoptosis induced by oxidative stress in human neuroblastoma SH-SY5Y cells. Bioorg Med Chem 12:15CrossRefGoogle Scholar
  3. Alexander M et al (1979) Therapeutic use of albumin. J Am Med Assoc 241:2527–2529Google Scholar
  4. Altman GH et al (2003) Silk-based biomaterials. Biomaterials 24:401–416Google Scholar
  5. Antoon C, Kirsch J (1982) Investigation of diffusion-limited rates of chymotrypsin reactions by viscosity variation. Biochemistry 21:1302–1307Google Scholar
  6. Arora R et al (2009) Epidemiology of childhood cancer in India. Ind J Cancer 46:257–259Google Scholar
  7. Athanssiadou S et al (2001) Direct antihelminthic effects of condensed tannings towards different gastrointestinal nematodes of sheep: in vitro and in vivo studies. Vet Parasitol 99:205–219Google Scholar
  8. Azhar M, Sara T (2004) Comparison of nerve graft and artificial conduits for bridging nerve defects. Med J Malays 59:578–584Google Scholar
  9. Azman K et al (2011) Antiobesity effect of Tamarindus indica L. pulp aqueous extract in high-fat diet-induced obese rats. J Natl Med 66:22Google Scholar
  10. Bae Y et al (2011) Coconut-derived D-xylose affects postprandial glucose and insulin responses in healthy individuals. Nutr Res Pract 5:5Google Scholar
  11. Battiston B et al (2005) Nerve repair by means of tubulization: literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair. Microsurgery 25:258–267Google Scholar
  12. Bednar H et al (1982) Preliminary findings using wood as an implant material. In: Winter GD, Gibbons DF, Plenk Jr H (eds) Biomaterials 1980. Wiley, New YorkGoogle Scholar
  13. Bellamkonda R (2006) Peripheral nerve regeneration: an opinion on channels, scaffolds and anisotropy. Biomaterials 27:3515–3518Google Scholar
  14. Bentley P, Parekh A (1998) Perceptions of anemia and health seeking behavior among women in four Indian states.” MotherCare/John Snow, Inc, WashingtonGoogle Scholar
  15. Bharathi M et al (2009) Analysis of the risk factors predisposing to fungal, bacterial & Acanthamoeba keratitis in south India. Ind J Med Res 130:749–7Google Scholar
  16. Bhardwaj N et al (2011) Silk protein as biomaterial for tissue engineering and regenerative medicine, New visions for biomaterials and regenerative medicine (Workshop). 16–17 March 2011Google Scholar
  17. Bhaskar J et al (2011) Beneficial effects of banana (Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats. J Physiol Biochem 67:8CrossRefGoogle Scholar
  18. BioSpectrum Bureau (2011) Boston Scientific launches stent systems in India. BioSpectrum: Asia Edition, 21 February 2011Google Scholar
  19. Brown B (1988) Hematology: principles and procedures. Lea and Febiger, PhiladelphiaGoogle Scholar
  20. Burgalassi S et al (1999) Development of a simple dry eye model in the albino rabbit and evaluation of some tear substitutes. Ophthalmic Res 31:229–235Google Scholar
  21. Campbell-Falck D (2000) The intravenous use of coconut water. Am J Emerg Med 18:108–111Google Scholar
  22. Carvalho F et al (2011) The recognition of N-Glycans by the lectin ArtinM mediates cell death of a human myeloid leukemia cell line. PLoS One 6:e27892Google Scholar
  23. Chalfoun C et al (2006) Tissue engineered nerve constructs: where do we stand? J Cell Mol Med 10:309–317Google Scholar
  24. Chandramohan D, Marimuthu K (2011) Characterization of natural fibers and their application in bone grafting substitutes. Acta Bioeng Biomech 13:25Google Scholar
  25. Chandran A et al (2010) The Global burden of unintentional injuries and an agenda for progress. Epidemiol Rev 32:22CrossRefGoogle Scholar
  26. Chandy T, Sharma CP (1993) Preparation and performance of chitosan encapsulated activated charcoal (ACCB) adsorbents for small molecules. J Microencapsul 10:475–486Google Scholar
  27. Chandy T, Sharma CP (1998) Activated charcoal microcapsules and their applications. J Biomater Appl 13:128–157Google Scholar
  28. Charnot Y, Peres G (1978) Silicon and bone mineralization. In: Bendx G, Lindquist I (eds) Biochemistry of silicon and related problems. Plenum, New YorkGoogle Scholar
  29. Chen M et al (2006) Luminal fillers in nerve conduits for peripheral nerve repair. Ann Plast Surg 57:462–471Google Scholar
  30. Chirila TV et al (2008) Bombyx mori Silk fibroin membranes as potential substrata for epithelial constructs used in the management of ocular surface disorders. Tissue Eng Part A 14:1203–1211Google Scholar
  31. Constantinides PP (1995) Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects. Pharm Res. 12:1561–1572Google Scholar
  32. Dandona L et al (1998) Causes of corneal graft failure in India. Ind J Ophthalmol 46:149–52Google Scholar
  33. Dangas G et al (2010) In-Stent Restenosis in the Drug-Eluting Stent Era. J Am Coll Cardiol 56:1897–1907 Google Scholar
  34. Das A et al (2009) Protective effect of Corchorus olitorius leaves against arsenic-induced oxidative stress in rat brain. Environ Toxicol Pharmacol 29:6Google Scholar
  35. Das S et al (2011) Determination of Anthelmintic Activity of the Leaf and Bark Extract of Tamarindus Indica Linn. Ind J Pharm Sci 73:30CrossRefGoogle Scholar
  36. Davis E et al (2011) New anticoagulant therapy for atrial fibrillation and ACS: oral direct thrombin inhibitors. Pharmacotherapy 31:1208–1220Google Scholar
  37. de Silva N et al (2003) Soil-Transmitted Helminthic Infections: Updating the global picture. Disease control priorities Project. July 2003Google Scholar
  38. Dhingra N et al (2010) Adult and child malaria mortality in India: a nationally representative mortality survey. Lancet 376: 1768–1774Google Scholar
  39. Diebold Y, Calonge M (2010) Applications of nanoparticles in ophthalmology. Progr Retin Eye Res 29:596–609Google Scholar
  40. Doughari J (2006) Antimicrobial activity of Tamarindus indica Linn. Trop J Pharm Res 5:597–603Google Scholar
  41. Duvvuri S et al (2003) Drug delivery to the retina: challenges and opportunities. Expert Opin Biol Ther 3:45–56Google Scholar
  42. Ebel B et al (2010) Burn injury and the impact on global health. Inj Prev 16:389–392Google Scholar
  43. Eiseman B (1954) Intravenous infusion of coconut water. Am Med Assoc Arch Surg 68:167–178Google Scholar
  44. Encyclopaedia Britannica (2012) Coloration.” Encyclopaedia Britannica Online Academic Edition. Accessed 25 March 2012
  45. Erstad B (1996) Viral infectivity of albumin and plasma protein fraction. Pharmacotherapy 16:996–1001Google Scholar
  46. Eye Bank Association of America (2005) Annual report, 2005Google Scholar
  47. Fernando M et al (1991) Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients. J Ethnopharmacol 31:277–282Google Scholar
  48. Garcia ML et al (2009) Composition, industrial processing and applications of rice bran γ-oryzanol. Food Chem. 115:389–404Google Scholar
  49. Gavin J (2001) Pathophysiologic mechanisms of postprandial hyperglycemia. Am J Cardiol 88:4–8Google Scholar
  50. Georgea A, Larkin D (2004) Corneal transplantation: the forgotten graft. Am J Transpl 4:678–685Google Scholar
  51. Ghosh N, Singh R (2009) Groundwater arsenic contamination in India: vulnerability and scope for remedy. National Institute of Hydrology, UttarakhandGoogle Scholar
  52. Giavaresi G et al (2009) Bone regeneration potential of a soybean-based filler: experimental study in a rabbit cancellous bone defects. J Mater Sci 21:22Google Scholar
  53. Gibbs B et al (2004) Production and characterization of bioactive peptides from soy hydrolysate and soy-fermented food. Food Res Int 37:123–131Google Scholar
  54. Gore M, Akolekar D (2003) Evaluation of banana leaf dressing for partial thickness burn wounds. Burns 29:487–492Google Scholar
  55. Gourie-Devi M (2008) Organization of neurology services in India: unmet needs and the way forward. Neurology India 56:4–12 Google Scholar
  56. Government of India. “Chapter 7: Nutrition and the Prevalence of Anaemia.” From National Family Health Survey-2. Website:
  57. Greenwood H et al (2006) Regenerative medicine and the developing world. PLoS Med 3:e381Google Scholar
  58. Gupta J et al (2010) National programme for prevention of burn injuries. Ind J Plast Surg 43:126–130Google Scholar
  59. Hamlyn P, Schmidt R (1994) Potential therapeutic application of fungal filaments in wound management. Mycologist 8:147–152Google Scholar
  60. Hanson S (1998) Blood-material interactions. In: Black J (ed) Handbook of biomaterial properties. Chapman & Hall, New YorkGoogle Scholar
  61. Hastings, G Wolf P (1992) The therapeutic use of albumin. Arch Family Med 1:1023–1026Google Scholar
  62. Haynes RJ, Tighe PJ, Dua HS (1999) Antimicrobial defensin peptides of the human ocular surface. Br J Ophthalmol 83:737–741Google Scholar
  63. Hazari A et al (1999) A resorbable nerve conduit as an alternative to nerve autograft in nerve gap repair. Br J Plast Surg 52:653–657Google Scholar
  64. He Y (2011) Large-scale production of functional human serum albumin from transgenic rice seeds. Proc Natl Acad Sci USA 108:22CrossRefGoogle Scholar
  65. Hedberg E et al (2005) In vivo degradation of porous poly(propylene fumarate)/poly(DL-lactic-co-glycolic acid) composite scaffolds. Biomaterials 26:3215Google Scholar
  66. Hsieh M et al (2010) Synthesis, in vitro macrophage response and detoxification of bamboo charcoal beads for purifying blood. J Biomed Mater Res Part A 94A:1133–1140 Google Scholar
  67. Hsieh M et al (2007) Application of bamboo charcoal particles in blood purification: cytotoxicity and absorption capability assessments. J Med Biol Eng 27:47–51Google Scholar
  68. Hu X, Lui W, Cui L, Wang M, Cao Y (2005) Tissue engineering of nearly transparent corneal stroma. Tissue Eng 11:1710–1717Google Scholar
  69. Huang N (2004) High-level protein expression system uses self pollinating crops as host. BioProcess Int 2:54–59Google Scholar
  70. Huang W et al (2012) Regenerative potential of silk conduits in repair of peripheral nerve injury in adult rats. Biomaterials 33:59–71Google Scholar
  71. IAEA RCA (2003) Workshop on radiation processing of natural polymers for healthcare applications.
  72. Ito Y et al (2006) Lig-8, a bioactive lignophenol derivative from bamboo lignin, protects against neuronal damage in vitro and in vivo. J Pharmacol Sci 102:196–204Google Scholar
  73. Jaykus L et al (2009) Food-borne microbes: shaping the host ecosystem. ASM Press, WashingtonGoogle Scholar
  74. Jha P et al (2010) HIV mortality and infection in India: estimates from nationally representative mortality survey of 1.1 million homes. Br Med J 340:c621Google Scholar
  75. Jin H et al (2005) Water-stable silk films with reduced beta-sheet content. Adv Funct Mate 15:1241–1247Google Scholar
  76. Joint United Nations Programme On HIV/AIDS (2008) Report on the global AIDS epidemic, 2008Google Scholar
  77. Joshi S, Parikh R (2007) India— diabetes capital of the World: now heading towards hypertension. J Assoc Physicians India 55:323–324Google Scholar
  78. Joshi S et al (2012) Prevalence of diagnosed and undiagnosed diabetes and hypertension in India—results from the screening India’s Twin Epidemic (SITE) Study. Diabetes Technol Ther 14:8–15Google Scholar
  79. Joshipura M (2008) Trauma care in India: current scenario. World J Surg 32:1613–1617Google Scholar
  80. Kaiser Family Foundation (2011). The global HIV/AIDS epidemic. Accessed 5 Feb 2012
  81. Kaur H et al (2011) Carboxymethyl tamarind kernel polysaccharide nanoparticles for ophthalmic drug delivery. Int J Biol Macromol 50:19Google Scholar
  82. Kawai N et al (1997) Bone formation by cells from femurs cultured among three-dimensionally arranged hydroxyapatite granules. Biomed Mater Res 37:1–8Google Scholar
  83. Kim I et al (2002) Effect of roasting temperature and time on the chemical composition of rice germ oil. JAOCS 79:413–418 Google Scholar
  84. Kittipongpatana N et al (2011) Preparation of cross-linked carbomethyl jackfruit starch and evaluation as a tablet disintegrant. Pak J Pharm Sci 24: 415–420Google Scholar
  85. Klemm R et al (2011) Are we making progress on reducing Anemia in Women? The USAID Micronutrient and Child Blindness Project. June 2011Google Scholar
  86. Kosuwon W et al (1994) Charcoal bamboo as a bone substitute: an animal study. J Med Assoc Thail 77:496–500Google Scholar
  87. Kundu J et al (2010) Silk fibroin nanoparticles for cellular uptake and control release. Int J Pharm 388:8CrossRefGoogle Scholar
  88. Lamien-Meda A et al (2008) Polyphenol content and antioxidant activity of fourteen wild edible fruits from Burkina Faso. Molecules 13:6CrossRefGoogle Scholar
  89. Langer R, Vacanti J (1993) Tissue engineering. Science 260:14CrossRefGoogle Scholar
  90. Lawrence B et al (2008) Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules 9:12CrossRefGoogle Scholar
  91. Lawrence B et al (2009) Silk film biomaterials for corneal tissue engineering. Biomaterials 30:1299–1308CrossRefGoogle Scholar
  92. Lewis D et al (1999) A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions. J Ethnopharmacol 65:7CrossRefGoogle Scholar
  93. Li SH et al (1996) Biomimetic coating of bioactives ceramic on bamboo for biomedical applications. J Mater Sci Lett 15:1882–1885Google Scholar
  94. Li SH et al (1997) In vitro calcium phosphate formation on a natural composite material, bamboo. Biomaterials 18:389–395Google Scholar
  95. Li Y et al (2008) Paste viscosity of rice starches of different amylose content and carboxymethylcellulose formed by dry heating and the physical properties of their films. Food Chem 109:1CrossRefGoogle Scholar
  96. Lin C et al (2010) A selectively terminable transgenic rice line expressing human lactoferrin. Protein Expr Purif 74:28CrossRefGoogle Scholar
  97. Liu H et al (2007) Modification of Sericin-free silk fibers for ligament tissue engineering application. Wiley InterScienceGoogle Scholar
  98. Luduena L et al (2011) Nanocellulose from rice husk following alkaline treatment to remove silica. BioResources 6:1440–1453Google Scholar
  99. Mandal B, Kundu S (2009a) Calcium alginate beads embedded in silk fibroin as 3D dual drug releasing scaffolds. Biomaterials 30:23Google Scholar
  100. Mandal B, Kundu S (2009b) Self-assembled silk sericin/poloxamer nanoparticles as nanocarriers of hydrophobic and hydrophilic drugs for targeted delivery. Nanotechnology 20:11CrossRefGoogle Scholar
  101. Mandal B et al (2009) Silk fibroin/polyacrylamide semi-interpenetrating network hydrogels for controlled drug release. Biomaterials 30:8CrossRefGoogle Scholar
  102. Manjanna K et al (2009) Diclofenac sodium microbeads for oral sustained drug delivery. Int J PharmTech Res 1:317–327Google Scholar
  103. Mannucci LL, Fregona I, Di Gennaro A (2000) Use of a new lachrymal substitute (T S Polysaccharide) in Contactology. J Med Contactology Low Vis 1:6–9Google Scholar
  104. Mayo Clinic Staff (2012) “Sepsis.” Mayo Clinic Health Information. Accessed 24 March 2012
  105. McClellan K (1997) Mucosal defense of the outer eye. Surv Ophthalmol 42:233–246Google Scholar
  106. Meagher J et al (2005) Crystal structure of banana lectin reveals a novel second sugar binding site. Glycobiology 15:8CrossRefGoogle Scholar
  107. Mehlhorn H (ed) (2008) Encyclopedia of parasitology, 3rd edn. Springer, New YorkGoogle Scholar
  108. Mehlhorn H et al (2010) Addition of a combination of onion (Allium cepa) and coconut (Cocos nucifera) to food of sheep stops gastrointestinal helminthic infections. Parasitol Res 108:1Google Scholar
  109. Meinel L et al (2005a) Silk implants for the healing of critical size bone defects. Bone 37:22CrossRefGoogle Scholar
  110. Meinel L et al (2005b) The inflammatory responses to silk films in vitro and in vivo. Biomaterials 26:147–155Google Scholar
  111. Mekkriengkrai D et al (2004) Structural characterization of rubber from jackfruit and euphorbia as a model of natural rubber. Biomacromolecules 5:2013-2019Google Scholar
  112. Mesfin A et al (2011) Ethnobotanical study of antimalarial plants in Shinile District, Somali Region, Ethiopia, and in vivo evaluation of selected ones against Plasmodium berghei. J Ethnopharmacol 139:11Google Scholar
  113. Mieszawska AJ et al (2011) Clay enriched silk biomaterials for bone formation. Acta Biomaterialia 7: August 2011
  114. Miller E, Ullrey D (1987) The pig as a model for human nutrition. Ann Rev Nutr 7:361–382Google Scholar
  115. Misquith S et al (1994) Carbohydrate binding specificity of the B-cell maturation mitogen from Artocarpus Intergrifolia seeds. J Biol Chem 269:30393–30401Google Scholar
  116. Mollichelli N et al (2010) Prolonged Double Antiplatelet Therapy in a Cohort of “De Novo” Diabetic Patients Treated with Drug-Eluting Stent Implantation. Am J Cardiol 105:15CrossRefGoogle Scholar
  117. Naskar S (2011) Evaluation of antihyperglycemic activity of Cocos nucifera Linn. on streptozotocin induced type 2 diabetic rats. J Ethnopharmacol 138:20CrossRefGoogle Scholar
  118. Natural Resources Defense Council (2009) Arsenic in drinking water. Accessed 2 Feb 2009
  119. Nayak AK et al (2010) Evaluation of Spinacia oleracea L. leaves mucilage as an innovative suspending agent. Chemistry 19: 338–341Google Scholar
  120. Nayak A, Pal D (2011) Development of pH-sensitive tamarind seed polysaccharide-alginate composite beads for controlled diclofenac sodium delivery using response surface methodology. Int J Biol Macromol 49:23CrossRefGoogle Scholar
  121. Nneli R, Woyike O (2008) Antiulcerogenic effects of coconut (Cocos nucifera) extract in rats. Phytother Res 22:3CrossRefGoogle Scholar
  122. Neena J et al (2008) Rapid assessment of avoidable blindness in India study group. PLoS One 3:e2867Google Scholar
  123. Ojewole J, Adewunmi C (2003) Hypoglycemic effect of methanolic extract of Musa paradisiaca (Musaceae) green fruits in normal and diabetic mice. Methods Find Exp Clin Pharmacol 25:453–456Google Scholar
  124. Oliveira AL et al (2012) Aligned silk-based 3-D architectures for contact guidance in tissue engineering. Acta Biomaterialia 8:1530–1542 Google Scholar
  125. Otaigbe J (1998) Controlling the water absorbency of agricultural biopolymers. Plast Eng 54:37Google Scholar
  126. Ouyang Q, Tandon R, Gol KL et al (2005) The emergence of inflammatory bowel disease in the Asian Pacific region. Curr Opin Gastroenterol 21:408–413Google Scholar
  127. Pari L, Umamaheshwari J (2000) Antihyperglycemic activity of Musa sapientum flowers: effect on lipid peroxidation in alloxan diabetic rats. Phytother Res 14:1–3Google Scholar
  128. Pawar S, Vavia P (2012) Rice germ oil as multifunctional excipient in preparation of self-microemulsifying drug delivery system (SMEDDS) of tacrolimus. AAPS Pharm Sci Tech 13:10CrossRefGoogle Scholar
  129. Peters T (1995) All about albumin: biochemistry, genetics, and medical applications. Academic, San DiegoGoogle Scholar
  130. Petroianu G et al (2004) Green coconut water for intravenous use: trace and minor element content. J Trace Elem Exp Med 17:30CrossRefGoogle Scholar
  131. Poritz L et al (2007) Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis. J Surg Res 140:1CrossRefGoogle Scholar
  132. Prabaharan M et al (2007) Preparation and characterization of poly(L-lactic acid)-chitosan hybrid scaffolds with drug release capability. J Biomed Mater Res B: Appl Biomater 81 B:427–434Google Scholar
  133. Pummer S et al (2001) Influence of coconut water on hemostasis. Am J Emerg Med 19:287-289Google Scholar
  134. Punyanitya S (2010) Absorbable suture made from rice starch. Adv Mater Res 123–125Google Scholar
  135. Rahman M et al (2006) Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion. Hemodial Int 10:256–259Google Scholar
  136. Reddy K (2007) India wakes up to the threat of cardiovascular diseases. J Am Coll Cardiol 50:1370–1372Google Scholar
  137. Reed T (2010) Protein in bananas could help block spread of HIV, University of Michigan researchers say. Ann Arbor, 15 March 2010Google Scholar
  138. Riesle J et al (1998) Collagen in tissue-engineered cartilage: types, structure, and crosslinks. J Cell Biochem 71:1CrossRefGoogle Scholar
  139. Rimondini L et al (2005) In vivo experimental study on bone regeneration in critical bone defects using an injectable biodegradable PLA/PGA copolymer.” Oral Surg Oral Med Oral Pathal Oral Radiol Endotol 99:148–154Google Scholar
  140. Rony K et al (2011) Ganoderma lucidum (Fr.) P. Karst occurring in South India attenuates gastric ulceration in rats. Ind J Nat Prod Resour 2: 19–27Google Scholar
  141. Sahoo R et al (2010a) Release behavior of anticancer drug paclitaxel from tamarind seed polysaccharide galactoxyloglucan. Eur J Sci Res 47:197–206Google Scholar
  142. Sahoo S et al (2010b) Mucoadhesive nanopolymer—a novel drug carrier for topical ocular drug delivery. Eur J Sci Res 46:401–409Google Scholar
  143. Sahoo S et al (2011) Tamarind seed polysaccharide: a versatile biopolymer for mucoadhesive applications. J Pharm Biomed Sci 8:8Google Scholar
  144. Sambu S, Wilson R (2008) Arsenic in food and water—a brief history. Toxicol Ind Heal 24:217–226Google Scholar
  145. Sanghavi P (2009) Fire-related deaths in India in 2001: a retrospective analysis of data. Lancet 373:1282–1288Google Scholar
  146. Sankar M et al (2008) Sepsis in the Newborn. Ind J Pediatr 75(3):261–266Google Scholar
  147. Santin M et al (2007) A new class of bioactive and biodegradable Soybean-based bone fillers. Biomacromolecules 8:7CrossRefGoogle Scholar
  148. Schlosshauer B et al (2006) Synthetic nerve guide implants in humans: a comprehensive survey. Neurosurgery 59:740–748Google Scholar
  149. Segalla S et al (2001) Retinoic acid receptor fusion to PML affects its transcriptional and chromatin-remodeling properties. Mol Cell Biol 23:8795–8808Google Scholar
  150. Seri K et al (1996) L-arabinose selectively inhibits intestinal sucrase in an uncompetitive manner and suppresses glycemic response after sucrose ingestion in animals. Metabolism 45:1368–1374Google Scholar
  151. Shih M et al (2010) Characterization of two soy bean (Glycine max L.) LEA IV proteins by circular dichroism and Fourier transform infrared spectrometry. Plant Cell Physiol 51:395–407Google Scholar
  152. Siritapetawee J, Thammasirirak S (2011) Purification and characterization of a heteromultimeric glycoprotein from Artocarpus heterophyllus latex with an inhibitory effect on human blood coagulation. Acta Biochim Pol 58:30Google Scholar
  153. Sofia S et al (2001) Functionalized silk-based biomaterials for bone formation. J Biomed Mater Res 54:3162–3166Google Scholar
  154. Swanson M et al (2010) A lectin isolated from bananas is a potent inhibitor of HIV replication. J Biol Chem 285:19CrossRefGoogle Scholar
  155. Takahashi T (2011) Flow behavior of digesta and the absorption of nutrients in the gastrointestine. J Nutr Sci Vitaminol 57:265–273Google Scholar
  156. Takahashi T, Sakata T (2005) Insoluble dietary fibers: the major modulator for the viscosity and flow behavior of digesta. Foods Food Ingred J Jpn 210:944–953Google Scholar
  157. Takahashi T et al (2005) Crystalline cellulose reduces plasma glucose concentrations and stimulates water absorption by increasing the digesta viscosity in rats. J Nutr 135:2405–2410Google Scholar
  158. Takahashi T et al (2009) Water-holding capacity of insoluble fibre decreases free water and elevates digesta viscosity in the rat. J Sci Food Agric 89:177–194Google Scholar
  159. Taylor H (1999) Epidemiology of age-related cataract. Eye 13:445–448Google Scholar
  160. Thompson D, Geary T (1995) The structure and function of helminth surfaces. In: Marr J (ed) Biochemistry and molecular biology of parasites. Academic Press, New YorkGoogle Scholar
  161. Tongdang T (2008) Some properties of starch extracted from three Thai aromatic fruit seeds. Starch/Starke 60:199–207Google Scholar
  162. Tsuchida E et al (2009) Artificial oxygen carriers, hemoglobin vesicles and albumin-hemes, based on bioconjugate chemistry. Bioconjugate Chem 20:1419–1440Google Scholar
  163. UNICEF/WHO (2009) Diarrhoea: Why children are still dying and what can be done.
  164. United Nations Development Project, India (2011) Responding to the HIV/AIDS challenge. Accessed 23 March 2012Google Scholar
  165. Varki A et al (eds) (1999) Essentials of glycobiology. Cold Spring Harbor Laboratory Press, Cold Spring HarborGoogle Scholar
  166. Wang Y et al (2006) Potent inhibition of fatty acid synthase by parasitic loranthus [Taxillus chinensis (dc.) Danser] and its constituent avicularin. J Enzym Inhib Med Chem 21:87–93Google Scholar
  167. Wang X et al (2008) Controlled release from multilayer silk biomaterial coatings to modulate vascular cell responses. Biomaterials 29:894–903Google Scholar
  168. Watts C (2002) The public health impact of microbicides: model projections.
  169. Welcker K et al (2004) Increased intestinal permeability in patients with inflammatory bowel disease. Eur J Med Res 9:29Google Scholar
  170. Whysner J, Williams GM (1996) Butylated hydroxyanisole mechanistic data and risk assessment: conditional species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. Pharmacol Ther 71:153–191Google Scholar
  171. World Health Organization (2010) Injuries and violence: the facts. Accessed 22 March 2012
  172. Wu S et al (2009) Preparation of porous 45S5 Bioglass®-derived glass-ceramic scaffolds by using rice husk as a porogen additive. J Mater Sci 20:22Google Scholar
  173. Xinhua News Agency (2007) Drug watchdog tightens supervision of albumin medicine. April 4, 2007. Beijing Review. 60856.htm
  174. Xu W, Yang Y (2009) Drug sorption onto and release from soy protein fibers. J Mater Sci: Mater Med 20:17Google Scholar
  175. Yasuda K (2007) Effects of inulin on iron utilization by young anemic pigs and implications for human nutrition. A thesis presented to the Faculty of the Graduate School of Cornell University in Partial Fulfillment of the Requirements for the Degree of Master of Science. August 2007Google Scholar
  176. Young D et al (2011) Soy-derived di- and tripeptides alleviate colon and ileum inflammation in pigs with dextran sodium sulfate-induced Colitis. J Nutr 142:21Google Scholar
  177. Zhang Q et al (2004) Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efficiency to the brain. Int J Pharm 275:85–96Google Scholar
  178. Zhang W et al (2011) The use of injectable sonicatin-induced silk hydrogel for VEGF165 and BMP-2 delivery for elevation of the maxillary sinus floor. Biomaterials 32:1CrossRefGoogle Scholar
  179. Zaffe D et al (2005) Histological study on sinus lift grafting by Fisiograft and Bio-Oss. J Mater Sci: Mater Med 16:789–793Google Scholar

Copyright information

© The Author(s) 2013

Authors and Affiliations

  1. 1.School of Engineering and Applied ScienceHarvard UniversityCambridgeUSA

Personalised recommendations