Abstract
Acute myeloid leukemia (AML) is a systemic disease that is “metastatic” from diagnosis; therefore, the problems typically associated with local and regional control, i.e., those associated with surgery and radiation therapy, do not play a role. Since virtually all patients who die as a result of a malignant disease die of systemic (metastatic) cancer, AML has served as a prototype illness for the development of systemic therapies, and advances in the control of this disease have been rapidly applied to the control of the more common metastatic cancers in man.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Freireich EJ, Frei III E. Recent advances in acute leukemia. In: Moore CV, Brown EB, editors. Progress in hematology. New York: Grune and Stratton; 1964. p. 189–202.
Freireich EJ, Bodey GP, Hart JS, Rodriguez V, Whitecar JP, Frei III E. Remission induction in adults with acute myelogenous leukemia. In: Mathe G, editor. Recent results in cancer research, vol. 30. Berlin: Springer; 1970. p. 85–91.
Bodey GP, Hewlett JS, Coltman Jr CA, Rodriguez V, Freireich EJ. Therapy of adult acute leukemia with daunorubicin and L-asparaginase. Cancer. 1974;33:626–30.
McCredie KB, Bodey GP, Freireich EJ, Gutterman JU, Hester JP, Drewinko B. Adult leukemia. In: Clark RL, Howe CD, editors. Cancer patient care at M.D. Anderson Cancer Center. Chicago: Year Book Medical Publishers; 1976. p. 165–97.
Bodey GP, Freireich EJ, McCredie KB, et al. Prolonged remissions in adults with acute leukemia following late intensification chemotherapy and immunotherapy. Cancer. 1981;47:1937–45.
Keating MJ, McCredie KB, Bodey GP, Smith TL, Gehan E, Freireich EJ. Improved prospects for long-term survival in adults with acute myelogenous leukemia. JAMA. 1982;248:2481–6.
Keating MJ, Cork A, Broach Y, et al. Toward a clinically relevant cytogenetic classification of acute myelogenous leukemia. Leuk Res. 1987;11:119–33.
Freireich EJ. Four decades of therapy for acute myeloblastic leukemia. Leukemia. 1998;12 Suppl 1:S54–6.
Kantarjian H, O’Brien S, Cortes J, et al. Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years. Cancer. 2008;113(7):1933–52.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this chapter
Cite this chapter
Freireich, E.J. (2013). Acute Myeloid Leukemia. In: Rodriguez, M., Walters, R., Burke, T. (eds) 60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5197-6_19
Download citation
DOI: https://doi.org/10.1007/978-1-4614-5197-6_19
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-5196-9
Online ISBN: 978-1-4614-5197-6
eBook Packages: MedicineMedicine (R0)