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Bone Sarcoma pp 131–152Cite as

Rare Bone Sarcomas

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Part of the book series: MD Anderson Cancer Care Series ((MDCCS))

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Rare tumors of bone include chordoma, adamantinoma, hemangioendothelioma, hemangiopericytoma, low-grade fibrosarcoma of bone, and malignant fibrous histiocytoma (MFH). These are distinctive and interesting diseases with unique features. They bear some relationship to a spectrum of different mesenchymal tissues. Chordomas are probably derived from notochordal cells and thus are found primarily in the sacrum and sphenoocciput. Adamantinomas, on the other hand, are found predominantly in the tibia and show a peculiar tendency toward epithelial differentiation. The other tumors are more widely located within the body; hemangioendothelioma and hemangiopericytoma are tumors related to vascular tissue, whereas low-grade fibrosarcoma and MFH are most likely derived from spindle-shaped, fibroblast-like cells.

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Authors and Affiliations

  1. Department of Orthopaedic Oncology, Unit 1448, Division of Surgery, The University of Texas MD Anderson Cancer Center, 301402, Houston, TX, 77230, USA

    Valerae O. Lewis

  2. Department of Radiation Oncology, Unit 97, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA

    Ashleigh Guadagnolo

  3. Department of Neurosurgery, Unit 442, Division of Surgery, The University of Texas MD Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, TX, 77030, USA

    Laurence D. Rhines

  4. Department of Sarcoma Medical Oncology, Unit 450, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, TX, 77030, USA

    Shreyaskumar Patel

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  1. Valerae O. Lewis
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  2. Ashleigh Guadagnolo
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  4. Shreyaskumar Patel
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Correspondence to Valerae O. Lewis .

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Editors and Affiliations

  1. Division of Surgery, Department of Orthopedic Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, 77030, Texas, USA

    Patrick P. Lin

  2. Division of Cancer Medicine, Department of Sarcoma Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, 77030, Texas, USA

    Shreyaskumar Patel

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Lewis, V.O., Guadagnolo, A., Rhines, L.D., Patel, S. (2013). Rare Bone Sarcomas. In: Lin, P., Patel, S. (eds) Bone Sarcoma. MD Anderson Cancer Care Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-5194-5_8

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  • DOI: https://doi.org/10.1007/978-1-4614-5194-5_8

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