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Polymyositis

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Challenging Cases in Rheumatology and Diseases of the Immune System

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Abstract

Polymyositis (PM) is an inflammatory myopathy characterized by ­symmetric proximal muscle weakness with CD8+ T cells invading non-necrotic muscle fibers. Myositis-specific antibodies may serve as markers of clinical phenotype and treatment response. Statin use has been associated with precipitating an immune-mediated, necrotizing myositis. Herein, we present two cases that were challenging in diagnosis, treatment, and follow-up.

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Authors and Affiliations

  1. Division of Rheumatology, Department of Internal Medicine, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN, 55905, USA

    Uma Thanarajasingam M.D., Ph.D. & Floranne Ernste M.D.

Authors
  1. Uma Thanarajasingam M.D., Ph.D.
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  2. Floranne Ernste M.D.
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Correspondence to Uma Thanarajasingam M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Medicine, University of California, San Francisco, 812 Pollard Rd. Suite #5, Los Gatos, 95032, California, USA

    Massoud Mahmoudi

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Thanarajasingam, U., Ernste, F. (2013). Polymyositis. In: Mahmoudi, M. (eds) Challenging Cases in Rheumatology and Diseases of the Immune System. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5088-7_9

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  • DOI: https://doi.org/10.1007/978-1-4614-5088-7_9

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-5087-0

  • Online ISBN: 978-1-4614-5088-7

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