Immunizations in the Child with Inflammatory Bowel Disease
A substantial portion of children and young adults with inflammatory bowel disease (IBD) will be treated with immunosuppressive medications during some course in their disease, placing them at risk for opportunistic infections. Some of these infections may be preventable by vaccinations; therefore, it is important to make sure that patients are up to date with immunizations. Inactivated vaccines can be administered to patients with IBD regardless of immunosuppression status and are generally safe and effective. It is currently recommended not to administer live vaccines to patients with IBD being treated with immunosuppressive therapy, although varicella vaccine has been safely given with good immune response.
KeywordsHepatitis Corticosteroid Pneumonia Influenza Polysaccharide
Research has been funded by Thrasher Research Fund, Merck and Co., Inc., a grant for Training in Pediatric Gastroenterology and Nutrition (T32DK07477), and MO1-RR02172 from the National Center for Research Resources, National Institutes of Health to the Children’s Hospital Boston General Clinical Research Center.
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