Cytopreparation is the science of optimizing and standardizing the collection, preparation, and analysis of cytologic samples in ways that promote the detection of cells-of-interest and accurate interpretation of nuclear morphology. Cytopreparation as a science is based on a single overarching principle: when we make a microscopical preparation for cytopathology, we should try to understand what we are doing and why. Otherwise, we are examining cells that have been treated in unknown ways that may diminish their usefulness. The Elements of Style, the well-known little book of English style by Strunk and White, stated famously, “Make every word tell.”1 In the context of cytopreparation, the goal is to “make every cell tell.”
KeywordsUterine Cancer Cytologic Sample Cytologic Preparation Clinical Laboratory Improvement Amendment Interpretive Skill
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