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Astrovirus Pathogenesis

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Astrovirus Research

Abstract

Astrovirus represents a public health problem and is responsible for a large proportion of diarrhea and enteric illness in children, the elderly, and the immunocompromised. In spite of its impact on human health, little is known about astrovirus pathogenesis. There are many reasons for this including the lack of a suitable small animal model for infection. This chapter will summarize the current state of our knowledge on astrovirus pathogenesis.

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Acknowledgments

We would like to thank past and present members of the Schultz-Cherry laboratory for their ongoing discussions and support; and the following financial sources throughout the years: U.S. Poultry & Egg Association, Hartwell Foundation, the St. Jude Children’s Infection Defense Center funds, and ALSAC. Also, we acknowledge the generous support of the National Turkey Federation, various commercial turkey producers, and Southeast Poultry Research Laboratory, USDA-ARS, for supplying commercial turkey poults.

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Authors and Affiliations

  1. Department of Infectious Diseases, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA

    Victoria Meliopoulos Ph.D. & Stacey Schultz-Cherry Ph.D.

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  1. Victoria Meliopoulos Ph.D.
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  2. Stacey Schultz-Cherry Ph.D.
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Correspondence to Stacey Schultz-Cherry Ph.D. .

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  1. , Infectious Diseases, St Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, 38105, Tennessee, USA

    Stacey Schultz-Cherry

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Meliopoulos, V., Schultz-Cherry, S. (2012). Astrovirus Pathogenesis. In: Schultz-Cherry, S. (eds) Astrovirus Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4735-1_4

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