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Cancer Immunotherapy pp 17–44Cite as

T Cell and Antigen-Presenting Cell Subsets in the Tumor Microenvironment

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Abstract

The development of successful antitumor immunity depends upon cross talk and collaboration between multiple T cell and antigen-presenting cell subsets. In this chapter, we review and summarize current knowledge regarding the function, interactions, and prognostic significance of each of these populations, as well as their dependence upon one another within the tumor microenvironment.

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Authors and Affiliations

  1. Department of Surgery and Graduate Program in Immunology, University of Michigan, Ann Arbor, MI, 48109-0669, USA

    Cailin Moira Wilke & Weiping Zou

  2. Department of Surgery, University of Michigan, Ann Arbor, MI, USA

    Shuang Wei & Ilona Kryczek

  3. Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, China

    Lin Wang & Guobin Wang

  4. Department of Medicine, Renji Hospital, Shanghai Jiao-Tong University, Shanghai, China

    Jingyuan Fang

  5. University of Michigan Comprehensive Cancer Center and Graduate Program in Cancer Biology, Ann Arbor, MI, USA

    Weiping Zou

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  1. Cailin Moira Wilke
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  2. Shuang Wei
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  3. Lin Wang
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  4. Ilona Kryczek
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  5. Jingyuan Fang
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  7. Weiping Zou
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Correspondence to Weiping Zou .

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  1. San Antonio Cancer Center, Babcock Road 2040, San Antonio, 78229, Texas, USA

    Tyler J. Curiel

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Wilke, C.M. et al. (2013). T Cell and Antigen-Presenting Cell Subsets in the Tumor Microenvironment. In: Curiel, T. (eds) Cancer Immunotherapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4732-0_2

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