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Neuroimmune Mechanisms of Glia and Their Interplay with Alcohol Exposure Across the Lifespan

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Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Abstract

A plethora of studies demonstrate a link between alcohol consumption and altered immune activity in the central nervous system (CNS). Alcohol-induced immune activity has been observed in animal models of fetal alcohol syndrome, in binge models associated with adolescence and adulthood, and in chronic models of alcohol consumption in adults and aged animals. The purpose of this chapter is to provide an overview of studies analyzing alcohol effects on immune activity in the CNS throughout the lifespan.

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  1. Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, 4301 W. Markham, #846, Little Rock, AR, 72205, USA

    Paul D. Drew & Cynthia J. M. Kane Ph.D.

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  1. Paul D. Drew
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  2. Cynthia J. M. Kane Ph.D.
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Correspondence to Cynthia J. M. Kane Ph.D. .

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  1. National Institute on Alcohol Abuse and, Division of Neuroscience and Behavior, NIH, Fishers Lane 5635, Bethesda, 20892, Maryland, USA

    Changhai Cui

  2. National Institute on Alcohol Abuse and, Division of Neuroscience and Behavior, NIH, Fishers Lane 5635, Bethesda, 20892, Maryland, USA

    Lindsey Grandison

  3. National Institute on Alcohol Abuse and, Division of Neuroscience and Behavior, NIH, Fishers Lane 5635, Bethesda, 20892, Maryland, USA

    Antonio Noronha

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Drew, P.D., Kane, C.J.M. (2013). Neuroimmune Mechanisms of Glia and Their Interplay with Alcohol Exposure Across the Lifespan. In: Cui, C., Grandison, L., Noronha, A. (eds) Neural-Immune Interactions in Brain Function and Alcohol Related Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4729-0_11

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