Immunoglobulins in Mammary Secretions

  • W. L. Hurley
  • P. K. Theil


Immunoglobulins secreted in colostrum and milk by the lactating mammal are major factors providing immune protection to the newborn. Immunoglobulins in mammary secretions represent the cumulative immune response of the lactating animal to exposure to antigenic stimulation that occurs through interaction with the environment. Extensive species variability exists in how and when maternal immunoglobulins are transferred to the neonate. In addition, there is a range of mechanisms by which the transferred immunoglobulins may play a protective role in the neonate. This chapter reviews the immunoglobulins found in mammary secretions in the context of their diversity of structure, origin, mechanisms of transfer, and function.


Mammary Gland Passive Immunity Bovine Colostrum Transepithelial Transport Ungulate Species 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Animal SciencesUniversity of Illinois at Urbana-ChampaignUrbanaUSA
  2. 2.Department of Animal Health and BioscienceAarhus UniversityTjeleDenmark

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