Phylogenetic Variability of Serum Lipids and Lipoproteins in Nonhuman Primates Fed Diets with Different Contents of Dietary Cholesterol
The response of serum lipids and lipoproteins to different levels of dietary cholesterol (0.05% to 1.5% w/w) was measured in six nonhuman primate species. Relative response of serum cholesterol in different species, measured in terms of response index, varied with dietary cholesterol concentration. The overall response for the different diets allowed ranking of the species as follows: Squirrel > green > spider ≃ rhesus ≃ patas > chimpanzee. The serum cholesterol response was reflected not only in an increase in β + pre-β-lipoprotein cholesterol but also in α-lipoprotein cholesterol, with significant differences among species in the amount of cholesterol transported in the lipoprotein classes.
KeywordsRhesus Monkey Serum Lipid Squirrel Monkey Dietary Cholesterol Spider Monkey
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