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Atherosclerosis Drug Discovery pp 65–75Cite as

Phylogenetic Variability of Serum Lipids and Lipoproteins in Nonhuman Primates Fed Diets with Different Contents of Dietary Cholesterol

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 67))

Abstract

The response of serum lipids and lipoproteins to different levels of dietary cholesterol (0.05% to 1.5% w/w) was measured in six nonhuman primate species. Relative response of serum cholesterol in different species, measured in terms of response index, varied with dietary cholesterol concentration. The overall response for the different diets allowed ranking of the species as follows: Squirrel > green > spider ≃ rhesus ≃ patas > chimpanzee. The serum cholesterol response was reflected not only in an increase in β + pre-β-lipoprotein cholesterol but also in α-lipoprotein cholesterol, with significant differences among species in the amount of cholesterol transported in the lipoprotein classes.

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Authors and Affiliations

  1. Dept. of Medicine, LSU School of Medicine and The Delta Primate Center of Tulane University, New Orleans, La, USA

    S. R. Srinivasan, C. C. Smith, B. Radhakrishnamurthy, R. H. Wolf & G. S. Berenson

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  1. S. R. Srinivasan
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  2. C. C. Smith
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  3. B. Radhakrishnamurthy
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  4. R. H. Wolf
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  5. G. S. Berenson
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Editors and Affiliations

  1. Atherosclerosis Research, The Upjohn Company, Kalamazoo, Michigan, USA

    Charles E. Day

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© 1976 Springer Science+Business Media New York

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Srinivasan, S.R., Smith, C.C., Radhakrishnamurthy, B., Wolf, R.H., Berenson, G.S. (1976). Phylogenetic Variability of Serum Lipids and Lipoproteins in Nonhuman Primates Fed Diets with Different Contents of Dietary Cholesterol. In: Day, C.E. (eds) Atherosclerosis Drug Discovery. Advances in Experimental Medicine and Biology, vol 67. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4618-7_3

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  • DOI: https://doi.org/10.1007/978-1-4614-4618-7_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9309-3

  • Online ISBN: 978-1-4614-4618-7

  • eBook Packages: Springer Book Archive

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