Effects of Cholesterol Derivatives on Sterol Biosynthesis
Atherosclerosis is a condition marked by the formation of plaques in the endothelium of the arterial system which in the earliest stage are composed largely of cholesterol. The etiology of the disease is not known, although it appears that an elevated serum cholesterol level may contribute to the development and the progression of atherosclerosis in animals and in man. The production of atherosclerotic lesions in experimental animals on a cholesterol-supplemented diet suggested a connection between cholesterol and atherosclerosis.
KeywordsPlasma Cholesterol Level Sterol Biosynthesis Sterol Synthesis Cholesterol Derivative Dietary Sterol
3-hydroxy-3-methylglutaryl Coenzyme A
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