Oxygen Diffusion and Atherosclerosis

  • Joseph D. Pool
  • John L. Gainer
  • Guy M. ChisolmIII
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 67)


That deprivation of oxygen may be a factor in atherogenesis is not a new theory. A review of the hypoxia phenomenon was presented by Heuper (1) in the mid 1940’s. He suggested that the common action of agents which cause vascular injury leading to edema or atherosclerosis is an interference with the oxidative metabolism of the vascular wall.


Oxygen Diffusion Sodium Cholate Rabbit Aorta Plasma Protein Level Systemic Hypoxia 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Joseph D. Pool
    • 1
  • John L. Gainer
    • 1
  • Guy M. ChisolmIII
    • 2
  1. 1.University of VirginiaCharlottesvilleUSA
  2. 2.Case Western UniversityClevelandUSA

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