Skip to main content
SpringerLink
Log in

Phospholipase A in Mitochondrial Membranes

  • Chapter
Membrane-Bound Enzymes

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 14))

Abstract

The study of the distribution of phospholipase A in subcellular organelles represents a way of approach to the understanding of membrane permeability. As a typical example it may be mentioned that, under appropriate conditions, lysophosphatides which result from the attack of phospholipids by phospholipase A induce a transition of the phospholipid structure from a lamellar to a micellar organization (1,2). This micellar reorganization of a lipid structure favors the fusion of juxtaposed membranes as recently shown by Howell and Lucy (3) in the case of erythrocyte membranes. It may be speculated that such reorganization also occurs at the level of the tight junctions in plasma membranes which, according to Benedetti and Emmelot (4), display a typical hexagonal mosaic pattern, and is responsible for the high permeability of those junction areas (5).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bangham, A.D. and Horne, R. W., J. Mol. Biol. 8: 660 (1964).

    Article  PubMed  CAS  Google Scholar 

  2. Hayden, D. A. and Taylor, J., Theoret. Biol. 4: 281 (1963).

    Article  Google Scholar 

  3. Howell, J. J. and Lucy, J. A., FEBS-Letters, 4: 147 (1969).

    Article  PubMed  CAS  Google Scholar 

  4. Benedetti, E. L. and Emmelot, P., in “Ultrastructure in Biological Systems” (A.J. Dalton and F. Hagueneau, Eds.) Vol. 7, p. 33, Academic Press, London and New-York (1968).

    Google Scholar 

  5. Loewenstein, W. R., Annals N. Y., Acad. Sci. 137: 441 (1966).

    Article  CAS  Google Scholar 

  6. Demel, R. A., Van Deenen, L. L. M. and Pethica, B. A., Bi.ochim. Biophys. Acta, 135: 11 (1967).

    Article  CAS  Google Scholar 

  7. Van Deenen, L. L. M., in “The molecular basis of membrane function” (D.C. Tosteson, Ed.), p. 47, Prentice Hall, New Jersey (1969).

    Google Scholar 

  8. Bangham, A. D., Standish, M. M. and Watkins, J. C., J. Mol. Biol. 13: 238 (1965).

    Article  PubMed  CAS  Google Scholar 

  9. Bangham, A. D., De Gier, J. and Greville, G. D., Chem. Phys. Lipids, 1: 225 (1967).

    Article  CAS  Google Scholar 

  10. Wattiaux, R., Wibo, M. and Baudhuin, P., in “Lysosomes” (A. V. S. De Reuck and M. P. Cameron, Eds.), p. 176, Ciba Foundation Symposium (1963).

    Google Scholar 

  11. Vignais, P. M. and Nachbaur, J., Bull. Soc. Chum. Biol. 50: 1473 (1968).

    CAS  Google Scholar 

  12. Vignais, P. M. and Nachbaur, J., Biochem. Biophys. Res. Comm. 33: 307 (1968).

    Article  CAS  Google Scholar 

  13. Vii*nais, P. M., Nachbaur, J., André, J, and Vignais, P. V., in “Mitochondria, Structure and Function” (L. Ernster and Z. Drahota, Eds.) Vol. 17, p. 43, FEBSSymposium, Academic Press, London and New-York (1969).

    Google Scholar 

  14. Parsons, D. F., Williams, G. R., Thompson, W.,, Wilson, D. and Chance, B., in “Mitochondrial Structure and compartmentation” (E. Quagliariello, S. Papa, E. C. Slater and. J. M. Tager, Eds.), p.9, Adriatica Editrice Bari (1967).

    Google Scholar 

  15. Molnar, J., Biochemistry, 6: 3067 (1967).

    Google Scholar 

  16. Appelmans, F., Wattiaux, R. and de Duve, C., Biochem. J. 59: 438 (1955).

    PubMed  CAS  Google Scholar 

  17. Tabor, C. W., Tabor, H. and Rosenthal, S. H., in “Methods in Enzymology” (S. P. Colowick and N. 0. Kaplan, Eds.), Vol. 2, p. 390, Academic Press, London and New-York (1955).

    Google Scholar 

  18. Linhardt, K. and Walter, K., in “Methods of Enzymatic Analysis” (H. U. Bergmeyer, Ed.) 2nd Edition, p.783, Verlag Chemie. (1965).

    Google Scholar 

  19. de Duve, C., Pressman, B. C., Gianetto, R., Wattiaux, R. and Appelmans, F., Biochem. J. 60: 604 (1955).

    CAS  Google Scholar 

  20. Omura, T., Siekevitz, P. and Palade, G. E., J. Biol. Chem. 242: 2389 (1967).

    PubMed  CAS  Google Scholar 

  21. Emmelot, P., Bos, C. J., Benedetti, E. L. and Rümke, Ph., Biochim. Biophys. Acta, 90: 126 (1964).

    Article  CAS  Google Scholar 

  22. Decloitre, F. and Chauveau, J., Bull. Soc. Chim. Biol, 50: 491 (1968).

    CAS  Google Scholar 

  23. Manganiello, V. C. and Phillips, A. P., J. Biol. Chem. 240: 3951 (1965).

    PubMed  CAS  Google Scholar 

  24. Leighton, F., Poole, B., Beaufay, H., Baudhuin, P., Coffey, J. W., Fowler, S. and de Duve, C., J. Cell. Biol. 37: 482 (1968).

    Article  PubMed  CAS  Google Scholar 

  25. Brunner, G. and Bygrave, F. L., European J, Biochem. 8: 530 (1969).

    Article  CAS  Google Scholar 

  26. Omura, T. and Sato, R., J. Biol. Chem. 239: 2370 (1964).

    PubMed  CAS  Google Scholar 

  27. Dawson, R. M. C., Hemington, N. and Lindsay, D. B., Biochem. J., 77: 226 (1960).

    PubMed  CAS  Google Scholar 

  28. Bartlett, G. R., J. Biol. Chem. 234: 466 (1959).

    PubMed  CAS  Google Scholar 

  29. Mattoon, J. R. and Sherman, F., J. Biol. Chem. 241: 4330 (1966).

    PubMed  CAS  Google Scholar 

  30. South, D. J. and Malher, H. R., Nature 218: 1226 (1968).

    Article  PubMed  CAS  Google Scholar 

  31. Van Deenen, L. L. M. and de Haas, G. H., Ann. Rev. Biochem. 35: 157 (1966).

    Article  Google Scholar 

  32. Goldfine, H., Ann. Rev. Biochem, 37: 303 (1968).

    Article  PubMed  CAS  Google Scholar 

  33. Lloveras, J., Douste Blazy, L. and Valdiguie, P., Compt. Rend. 256: 1851 (1963).

    Google Scholar 

  34. Rossi, C. R., Sartorelli, L., Tato, L., Baretta, L. and Siliprandi, N., Biochim. Biophys. Acta, 98: 207 (1965).

    Article  CAS  Google Scholar 

  35. Scherphof, G. L. and Van Deenen, L. L. M., Biochim, Biophys. Acta, 98: 204 (1965).

    CAS  Google Scholar 

  36. BjOrnstad, P., Lipid Res. 7: 612 (1966).

    CAS  Google Scholar 

  37. Waite, M. and Van Deenen, L. L. M,, Biochim. Biophys. Acta, 137: 498 (1967).

    Article  CAS  Google Scholar 

  38. Nachbaur, J. and Vignais, P. M., Biochim. Biophys. Res. Comm. 33: 315 (1968). 108 VIGNAIS, NACHBAUR, COLBEAU, AND VIGNAIS

    Google Scholar 

  39. Stoffel, W. and Greten, H., Hoppe Seyler’s physiol. chem. 348: 1145 (1968).

    Article  Google Scholar 

  40. Waite, M., Scherphof, G. L., Boshouwers, F. M. G. and Van Deenen, L. L. M., J. Lipid Res. 10: 411 (1969).

    PubMed  CAS  Google Scholar 

  41. Waite, M.,Biochemistry, 8: 2536 (1969)

    Article  CAS  Google Scholar 

  42. Bjdlrnstad, P., Biochim. Biophys. Acta, 116: 500 (1966).

    Article  Google Scholar 

  43. Scherphof, G. L., Waite, M. and Van Deenen, L. L. M., Biochim. Biophys. Acta, 125:406 (1966)

    Google Scholar 

  44. Slotboom, A. J., de Haas, G. H., Bonsen, P. P, M., Burdach-Westerhuis, G. J. and Van Deenen, L. L. M., Chem. Phys. of Lipids, 4: 15 (1970).

    Article  CAS  Google Scholar 

  45. Mellors, A. and Tappel, A. L., J. Lipid Res. 8: 479 (1967).

    PubMed  CAS  Google Scholar 

  46. Mellors, A., Tappel, A. L., Savant, P. L. and Desai, I. D., Biochim. Biophys. Acta, 143: 299 (1967).

    Article  CAS  Google Scholar 

  47. Smith, A. D. and Winkler, H., Biochem, J. 108: 867 (1968).

    CAS  Google Scholar 

  48. Blaschko, H., Smith, A. D., Winkler, H., Van den Bosch, H. and Van Deenen, L. L. M., Biochem. J. 103: 30C (1967).

    PubMed  CAS  Google Scholar 

  49. Winkler, H., Smith, A. D., Dubois, F. and Van den Bosch, H., Biochem. J. 105: 38C (1967).

    PubMed  CAS  Google Scholar 

  50. Rahman, Y. E., Verhagen, J. and Wiel, D., Biochim. Biophys. Res. Comm. 38: 670 (1970).

    Article  CAS  Google Scholar 

  51. Fowler, S. and de Duve, C., J. Biol. Chem. 244: 471 (1969).

    PubMed  CAS  Google Scholar 

  52. Lloveras, J. and Douste Blazy, L., Bull. Soc. Chim. Biol. 51: 67 (1969).

    Google Scholar 

  53. Gatt, S., Biochim. Biophys. Acta 159: 304 (1968).

    Article  CAS  Google Scholar 

  54. Van den Bosch, H., Aarsman, A. J., Slatboom, A, J. and Van Deenen, L. L. M., Biochim. Biophys. Acta, 164: 215 (1968).

    Article  Google Scholar 

  55. Hörtnagl, H., Winkler, H. and Hörtnagl, H., Europ. J. Biochem. 10: 243 (1969).

    Article  PubMed  Google Scholar 

  56. Leibovitz, Z. and Gatt, S., Biochim. Biophys. Acta, 164: 439 (1968).

    Article  CAS  Google Scholar 

  57. Van den Bosch, H., Van der Elzen, H. M,, and Van Deenen, L. L. M., Lipids, 2: 279 (1967).

    Article  Google Scholar 

  58. Letters, R., in “Aspects of yeast metabolism” (A. K. Mills and A. H. Krebs, Eds.) p. 303, Blackwell Scientific Publications, Oxford (1967).

    Google Scholar 

  59. Jollow, D., Kellerman, G. M. and Linnane, A. W., J. Cell. Biol. 37: 221 (1968).

    Article  PubMed  CAS  Google Scholar 

  60. Luckins, H. B., Jollow, D., Wallace, P. G. and Linnane, A. W., Aust. J. Exp. Biol. Med. Sci. 46: 651 (1968).

    Article  Google Scholar 

  61. Vignais, P. M., Nachbaur, J., Huet, J. and Vignais, P. V., Biochem. J. 116: 42P (1970).

    PubMed  CAS  Google Scholar 

  62. Stoffel, W. and Schiefer, H. G., Hoppe Seyler’s Physiol. Chem. 349: 1017 (1968).

    CAS  Google Scholar 

  63. Nachbaur, J., Colbeau, A. and Vignais, P. M., FEBSLetters 3: 121 (1969).

    Article  CAS  Google Scholar 

  64. Sarzala, M. G., Van Golde, L. M. de Kruyff, B. and Van Deenen, L. L. M., B.ochim. Biophys. Acta 202: 106 (1970).

    Article  CAS  Google Scholar 

  65. Eibl. H., Hill, E. E. and Lands, W. M. E., European J. Biochem. 9: 250 (1969).

    Article  Google Scholar 

  66. Norum, K. R., Farstad, M. and Bremer, J. Biochem. Biophys. Res. Comm., 24: 797 (1966).

    CAS  Google Scholar 

  67. Zborowski, J. and Wojtczak, L., Biochim. Biophys. Acta 187: 73 (1969).

    Article  CAS  Google Scholar 

  68. Shephard, E. H. and Hübscher, G., Biochem. J. 113: 429 (1969).

    PubMed  CAS  Google Scholar 

  69. Wirtz, K. W. A. and Zilversmit, D. B., J. Biol. Chem. 238: 2615 (1968).

    Google Scholar 

  70. Mc Murray, W. C. and Dawson, R. M. C., Biochem. J. 112: 91 (1969).

    CAS  Google Scholar 

  71. Akiyama, M. and Sakagami, T.,Biochim. Biophys. Acta, 187: 105 (1969).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Biochimie, Centre d’Etudes Nucléaires et Faculté de Médecine, 38-Grenoble, France

    P. M. Vignais, J. Nachbaur, A. Colbeau & P. V. Vignais

Authors
  1. P. M. Vignais
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Nachbaur
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Colbeau
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. V. Vignais
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Istituto di Chimica Biologica, Università di Pavia, 27100, Pavia, Italy

    Giuseppe Porcellati  & Fernando di Jeso  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Springer Science+Business Media New York

About this chapter

Cite this chapter

Vignais, P.M., Nachbaur, J., Colbeau, A., Vignais, P.V. (1971). Phospholipase A in Mitochondrial Membranes. In: Porcellati, G., di Jeso, F. (eds) Membrane-Bound Enzymes. Advances in Experimental Medicine and Biology, vol 14. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4616-3_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-4616-3_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0414-0

  • Online ISBN: 978-1-4614-4616-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation