Abstract
Membrane fractions isolated from cells which exhibit a potassium coupled active transport of sodium contain a (Na+ + K+)-activated enzyme system. This system fulfils so many of the requirements for a sodium-potassium transport system that it is reasonable to assume that the system is involved in the active trap port of the cations (see reviews by Skoul; Heinz2; Albers3; Glynn4).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Skou, J. C., Physiol. Rev. 45: 596 (1965).
Heinz, E., A. Rev. Physiol. 29: 21 (1967).
Albers, R. W., Ann. Rev. Biochem. 36: 727 (1967).
Glynn, I. M., Br. Med. Bull. 24:16(1968).
Glynn, I. M., J. Physiol. (Lond.) 160: 18P. (1962).
Laris, P. C. and Letchworth, P. E., J. Cell. Comp. Physiol. 60: 229 (1962).
Whittam, R., Biochem. J. 84: 110 (1962).
Garrahan, P. J. and Glynn, I. M., J. Physiol. (Lond.) 192:217 (1967 d).
Post, R. L., Merritt, C. R., Kinsolving, C. R., and Albright, C. D., J. Biol. Chem. 235: 1796 (1960).
Skou, J. C., in “The Molecular Basis of Membrane Function” (D. Tosteson, ed.), pp. 455–482, Prentice Hall, Inc., New Jersey (1969).
Skou, J. C. and Hilberg, C., Biochim. Biophys. Acta 185: 198 (1969).
Fahn, S., Koval, G. J., and Albers, R. W., J. Biol. Chem. 241: 18–82 (1966).
Post, R. L., Kume, S., Tobin, T., Orcutt, B., and Sen, A. K., J. Gen. Physiol. 54: 306 (1969).
Skou, J. C., Butler, K., and Hansen, 0., Biochim. Biophys. Acta
Matsui, H. and Schwartz, A., Biochim. Biophys. Acta 151: 655 (1968).
Albers, R. W., Koval, G. F., and Siegel, G. F., Mol. Pharmacol. 4: 324 (1968).
Sen, A. K., Tobin, T., and Post, R. L., J. Biol. Chem. 241: 6596 (1969).
Tobin, T. and Sen, A. K., Biochim. Biophys. Acta 198: 120 (1970).
Bader, H., Post, R. L., and Bond. E., Biochim. Biophys. Acta 150: 41 (1968).
Fahn, S., Koval, G. J., and Albers, R. W., J. Biol. Chem. 243: 1993 (1968).
Blostein, R., J. Biol. Chem. 245: 270 (1970).
Hokin, L. E., Sastry, P. S., Galsworthy, P. R., and Yoda, A., Proc. Nat. Acad. Sci. U.S.A. 54: 177 (1965).
Nagano, K., Kanazawa, T., Mizuno, N., Tashina, Y., Nakao, T., and Nakao, M., Biochem. Biophys. Res. Comm. 19: 759 (1965).
Bader, H., Sen, A. K., and Post, R. L., Biochim. Biophys. Acta 118: 106 (1966).
Schoner, W., Beusch, R., and Kramer, R., European J. Biochem. 7: 102 (1968).
Bond, G. H., Bader, H., and Post, R. L., Fed. Proc. 25: 567 (1966).
Israel, Y. and Titus, E., Biochim. Biophys. Acta 139: 450 (1967).
Interrusi, C. E. and Titus, E., Mol. Pharmacol. 6: 99 (1970).
Lindenmayer, G. E., Langhfer, A. H., and Schwartz, A., Arch. Biochem. Biophys. 127: 187 (1968).
Siegel, G. F., Koval, G. F., and Albers, R. W., J. Biol. Chem. 244: 32–64 (1969).
Hoffman, J. F., Fed. Proc. 19: 127 (1960).
Hoffman, J. F., Circulation 26: 1201 (1962).
Bader, H. and Sen, A. K., Biochim. Biophys. Acta 118: 116 (1966).
Mullins, L. F. and Brinley, F. J., J. Gen. Physiol. 53: 704 (1969).
Skou, J. C., Biochim. Biophys. Acta 42: 6 (1960).
Askari, A. and Koyal, D., Biochem. Biophys. Res. Comm. 32: 227 (1968).
Saito, M., in “Ann. Report Biol. Works”, pp. 15–47, published by Faculty of Science, Osaka Univ. (1969).
Ahmed, K. and Judah, J. D., Biochim. Biophys. Acta 104: 112 (1965).
Charnock, J. S. and Potter, H. A., Archiv. Biochem. Biophys. 134: 42 (1969).
Baker, P. F. and Stone, A. J., Biochim. Biophys. Acta 126: 321 (1966).
Shaw, T. J., Ph.D. Thesis, Cambridge University (1954).
Garrahan, P. J. and Glynn, I. M., J. Physiol. (Lond.).
Whittam, R., Wheeler, K. P., and Blake, A., Nature 203: 720 (1964).
Gruener, N. and Avi-Dor, Y., Biochem. J. 100: 762 (1966).
Mitchell, P., Advances in Enzymology. (Nord, F. F., ed.), vol. 29, pp. 33–87, Intersci. Publ., New York (1967).
Jardetzky, 0., Nature (London) 211:969 (1966).
Middleton, H. W., Arch. Biochem. Biophys. 136: 280 (1970).
Neufeld, A. H. and Levy, H. M., J. Biol. Chem. 244: 6493 (1969).
Sillén, L. G. and Martell, A. E., Stability Constants of Metal Ion Complexes. Special publication No. 17, London, The Chemical Society (1964).
NOrby, J. G., Acta Chem. Scand. (1970). In press.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1971 Springer Science+Business Media New York
About this chapter
Cite this chapter
Skou, J.C. (1971). The Role of the Phosphorylated Intermediate in the Reaction of the (Na+ + K+)-Activated Enzyme System. In: Porcellati, G., di Jeso, F. (eds) Membrane-Bound Enzymes. Advances in Experimental Medicine and Biology, vol 14. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4616-3_11
Download citation
DOI: https://doi.org/10.1007/978-1-4614-4616-3_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-0414-0
Online ISBN: 978-1-4614-4616-3
eBook Packages: Springer Book Archive