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The Relationship Between the Action of Tetanus Toxin and its Binding by Membranes and Gangliosides

  • Jane Mellanby
  • Diana Pope
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 71)

Abstract

Tetanus toxin binds to synaptic membranes and to purified gan-gliosides in vitro (van Heyningen, 1959, a, b, c). Two questions have frequently arisen: 1) are gangliosides responsible for the binding of tetanus toxin to nervous tissue?; and 2) does toxin binding play a role in the lethal action of the toxin?

Keywords

Botulinum Toxin Nervous Tissue Synaptic Membrane Tetanus Toxin Toxin Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Jane Mellanby
    • 1
  • Diana Pope
    • 1
  1. 1.Department of Experimental PsychologyUniversity of OxfordOxfordEngland

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