Distinct antagonistic effects of glucagon and insulin in the Embden-Meyerhof-chain

  • H. Schimassek
  • J. Helms
  • H. J. Mitzkat
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 2)


One of the important functions of the liver is to supply glucose for the entire organism and take up lactate from the whole body. Both these processes, i.e. the uptake of lactate and the supply of glucose, are very closely interconnected in the liver and there, coordination is obtained through hormonal control by glucagon. That means the essential effect of glucagon in the liver is not — as has been assumed so far — glycogenolysis but the reservai of the flow in the Embden-Meyerhof chain, in a word: gluconeo-genesis.


Flow Reversal Perfuse Liver Essential Effect Perfusion Experiment Entire Organism 
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Copyright information

© Springer Science+Business Media New York 1968

Authors and Affiliations

  • H. Schimassek
    • 1
  • J. Helms
    • 1
  • H. J. Mitzkat
    • 1
  1. 1.MarburgGermany

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