Abstract
Although hypothalamic LH- and FSH- releasing factors (LRF and FRF) have been discovered since 1960 (1, 2, 3, 4, 5) and 1964 (6, 7, 8) respectively, only a little work was done until now on their mechanism of action. Three possibilities at least can be envisaged (9): 1, a stimulation of excretion (or discharge) of hormone stored in the pituitary, 2. a direct or indirect action on synthesis of hormone in the appropriate cells, 3. an effedt on activation of hormonal precursors.
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References
HARRIS, E.W.., in Control of ovulation, C.A. VILLEE ed., Pergamon Press, London 1961, p. 56.
MCCANN, S.M., S. TALEISNIK and H.M. FRIEDMAN, Proc. Soc. Exptl. Biol. Med., 104: 432, 1960.
CAMPBELL, H.J., C. FEUER, G. GARCIA and G.W. HARRIS, J. Physiol., London, 157: 30P, 1961.
McCANN, S.M. and S. TALEISNIK, Endocrinology, 68: 1071, 1961.
COURRIER, R., R. GUILLEMIN, M. JUTISZ, E. SAKIZ and P. ASCHHEIM, C.R. Acad. Sc, Paris, 253: 922, 1961.
IGARASHI, M. and S.M. McCANN, Endocrinology, 74: 446, 1964.
MITTLER, J.C. and J. MEITES, Proc. Soc. Exptl. Biol. Med., 117: 309, 1964.
KUROSHIMA, A., Y. ISHIDA, C.Y. BOWERS and A.V. SCHALLY, Endocrinology, 76: 614, 1965.
JUTISZ, M., A. BERAULT, M.-A. NOVELLA and F. CHAPEVILLE, C.R. Acad. Sc., Paris, 263: Ser. D, 664, 1966.
GUILLEMIN, R., M. JUTISZ and E. SAKIZ, C.R. Acad. Sc., Paris, 256: 504, 1963.
JUTISZ, M., A. BERAULT, M.-A. NOVELLA and G. RIBOT, Acta Endocrinol., 55: 481, 1967.
SCHALLY, A.V. and C.Y. BOWERS, Endocrinology, 75: 312, 1964.
RAMIREZ, V.D. and S.M. McCANN, Endocrinology, 73: 193, 1963.
PARLOW, A.F., in Human pituitary gonadotropins. A. Albert ed., C.C. Thomas, Springfield, Ill., 1961, p. 300.
STEELMAN, S.L. and F.M. POHLEY, Endocrinology, 53: 604, 1953.
JUTISZ, M. and M.P. de la LLOSA, Endocrinology, accepted for publication.
de la LLOSA, P., C. COURTE and M. JUTISZ, Biochem. Biophys. Res. Commun., 26: 411, 1967.
JUTISZ, M. and M.P. de la LLOSA, C.R. Acad. Sc., Paris, 264: Ser. D, 118, 1967.
SAMLI, M.H. and I.I. GESCHWIND, Program of the 49th Meeting of the Endocrine Society, 1967, no.59.
DAVID, M.A., F. FRASCHINI and L. MARTINI, Experientia, 21: 483, 1965.
CORBIN, A. and J. STORY, Experientia, 22: 694, 1966.
KUROSHIMA, A., A. ARIMURA, T. SAITO, Y. ISHIDA, C.Y. BOWERS and A.V. SCHALLY, Endocrinology, 78: 1105, 1966.
SAITO, T., A. ARIMURA, E.E. MULLER, C.Y. BOWERS and A.V. SCHALLY, Endocrinology, 80: 313, 1967.
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Jutisz, M., Berault, A., de la Llosa, M.P. (1968). Studies on the Mechanism of Action of Hypothalamic FSH- and LH-Releasing Factors. In: Back, N., Martini, L., Paoletti, R. (eds) Pharmacology of Hormonal Polypeptides and Proteins. Advances in Experimental Medicine and Biology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4612-5_18
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DOI: https://doi.org/10.1007/978-1-4614-4612-5_18
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