Abstract
In 1966 Worthington described a method for the collection of hypophysial portal blood from the cut pituitary stalk of rats. This method was used (Fink, Nallar & Worthington, 1967) to demonstrate the presence of LRF in portal blood obtained from pro-oestrous and hypophysectomized rats. The possibility that the activity of portal plasma was due to vasopressin or a non specific factor was largely excluded, but it was pointed out that a significant proportion of the activity of portal plasma from prooestrus rats could have been due to LH contained in back-flow blood from the pituitary sinusoids.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Brown-Grant, K. (1967) J. Physiol. 190, 101.
Campbell, H.J., Feuer, G., Garcia, J., & Harris, G.W., (1961) J. Physiol. 157, 30p.
Chowers, I., & McCann, S.M. (1965) Endocrinology 76, 700.
Fawcett, C.P., Harris, G.W., & Reed, M., (1965) Proc. 23rd Intern. Cong. Physiol. Sci., Tokyo, 275.
Fink, G., Nallar, R., & Worthington, W.C.Jr. (1967) J. Physiol. 191, 407.
Grodsky, G.M., & Forsham, P.M., (1960) J. Clin. Invest. 39, 1071.
Guillemin, R., (1965) Proc. 23rd Intern. Cong. Physiol. Sci. Tokyo. 284.
Harris, G.W., Reed, M., & Fawcett, C.P., (1966) Brit. Med. Bull. 22, 266.
McCann, S.M. & Dhariwal, A.P.S. (1966). In Martini, L. & Ganong, W.F., Neuroendocrinology. New York; Academic Press.
Pelletier, J., (1964) C.r.hebd. Seanc.Acad.Sci. Paris. 258, 5979.
Pelletier, J., (1965) C.r.hebd. Seanc.Acad.Sci. Paris. 260, 5624.
Ramirez, V.D., & McCann, S.M., (1963) Endocrinology 73, 193.
Ramirez, V.D., & Sawyer, C.H., (1965) Endocrinology 76, 282.
Rothchild, I. (1965) Vitams. Horm. 23, 209.
Schally, A.V., & Bowers, C.Y. (1964) Endocrinology 75, 608.
Schmidt-Elmendorff, H., & Loraine, J.A., (1962) J. Endocr. 23, 413.
Worthington, W.C., Jr. (1966) Nature, Lond. 210, 710.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1968 Springer Science+Business Media New York
About this chapter
Cite this chapter
Fink, G. (1968). Studies on Luteinizing Hormone Releasing Factor (LRF) in Hypophysial Portal Blood of Rats. In: Back, N., Martini, L., Paoletti, R. (eds) Pharmacology of Hormonal Polypeptides and Proteins. Advances in Experimental Medicine and Biology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4612-5_17
Download citation
DOI: https://doi.org/10.1007/978-1-4614-4612-5_17
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-2726-2
Online ISBN: 978-1-4614-4612-5
eBook Packages: Springer Book Archive