Abstract
Biopharmaceutics operates at the interface of pharmaceutics and physiology. This chapter discusses observations and studies that emphasize the similarities and differences in species and routes of administration while providing references for notable reviews. The quintessential requirement of drug dissolution is discussed for immediate release formulations, and the use of biodegradable microspheres is reviewed for controlled release injectable formulations. From nasal and ocular to transdermal and oral, examples of formulations for veterinary practice are presented. If the formulation and the biopharmaceutics results in a well-absorbed drug product in one species, would it will behave similarly in other species? We can predict this when we have a sound understanding of the sometimes specie-specific physiology, and pharmaceutical knowledge of the formulation. With numerous routes of administration and preclinical studies already public knowledge, we may be on the brink of the golden age of veterinary pharmaceuticals.
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8th edition. © 2009, Elsevier
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Sutton, S.C. (2013). Biopharmaceutics and Veterinary Drug Delivery. In: Rathbone, M., McDowell, A. (eds) Long Acting Animal Health Drug Products. Advances in Delivery Science and Technology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4439-8_6
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DOI: https://doi.org/10.1007/978-1-4614-4439-8_6
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