Abstract
Iridocorneal endothelial (ICE) syndrome includes Chandler’s syndrome, progressive iris atrophy, and Cogan–Reese syndrome. These disorders usually occur in adults, more commonly in women. Unique clinical features include abnormalities of the corneal endothelium and iris, which can be detected by specular microscopy and clinical examination. Specular microscopy shows dark–light pattern reversal and reduced number of endothelial cells. Management of patients with ICE syndrome requires treatment for corneal edema, glaucoma, or both. The prevalence of glaucoma in ICE syndrome is high, and patients often require surgical treatment. Both trabeculectomy and glaucoma drainage implants have been used to treat glaucoma associated with ICE syndrome, but late failure may occur due to endothelialization of the bleb and obstruction of aqueous flow.
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Salim, S., Netland, P.A. (2014). Iridocorneal Endothelial Syndrome and Glaucoma. In: Samples, J., Schacknow, P. (eds) Clinical Glaucoma Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4172-4_20
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DOI: https://doi.org/10.1007/978-1-4614-4172-4_20
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