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Localized Surface Plasmon Resonance (LSPR) Transducers Based on Random Evaporated Gold Island Films: Properties and Sensing Applications

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Nanoplasmonic Sensors

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Abstract

Methods based on localized surface plasmon resonance (LSPR) spectroscopy have gained popularity in recent years, notably for label-free biosensing. This chapter summarized our progress in the development of LSPR transducers based on random evaporated gold island films. Systematic results on the preparation of Au island films with desired morphology and optical properties, as well as studies of the stability and sensitivity of such LSPR transducers, are presented. Schemes described here allowing tunability of the surface plasmon band wavelength, decay length and refractive index sensitivity of the LSPR transducers enable optimization of the transducer performance. Actual biosensing applications are exemplified using immunosensing (antigen-antibody interactions) and specific protein-carbohydrate interactions. It is concluded that random gold island films prepared by evaporation and annealing present a promising platform for the preparation of sensitive and cost-effective LSPR transducers offering scalability and simplicity.

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Authors and Affiliations

  1. Department of Materials and Interfaces, Weizmann Institute of Science, Rehovot, 76100, Israel

    Alexander Vaskevich & Israel Rubinstein

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  1. Alexander Vaskevich
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  2. Israel Rubinstein
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Correspondence to Alexander Vaskevich or Israel Rubinstein .

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  1. Dept. Applied Physics, Chalmers University of Technology, Fysikgränd 3, Göteborg, 412 96, Sweden

    Alexandre Dmitriev

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Vaskevich, A., Rubinstein, I. (2012). Localized Surface Plasmon Resonance (LSPR) Transducers Based on Random Evaporated Gold Island Films: Properties and Sensing Applications. In: Dmitriev, A. (eds) Nanoplasmonic Sensors. Integrated Analytical Systems. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3933-2_14

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