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An Introduction to Plasmonic Refractive Index Sensing

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Nanoplasmonic Sensors

Part of the book series: Integrated Analytical Systems ((ANASYS))

Abstract

This chapter introduces the basics of plasmon-based refractometric sensing, its application in label-free biomolecular analysis, and discusses differences between propagating plasmons and localized plasmons in terms of refractive index sensitivity, sensing volume and measurement methodology. Based on some recent nanoplasmonic sensing studies, we discuss plasmon–substrate interactions and the possibility to perform long-range nanoplasmonic sensing. We also discuss an experimental comparison between particle-based and thin film plasmonic biosensing, and we describe a method to enhance the sensitivity of nanoplasmonic sensing towards the single molecule limit using enzymatic signal amplification.

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Authors and Affiliations

  1. Department of Applied Physics, Chalmers University of Technology, Göteborg, 41296, Sweden

    Mikael Svedendahl, Si Chen & Mikael Käll

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  1. Mikael Svedendahl
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  2. Si Chen
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  3. Mikael Käll
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Correspondence to Mikael Käll .

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Editors and Affiliations

  1. Dept. Applied Physics, Chalmers University of Technology, Fysikgränd 3, Göteborg, 412 96, Sweden

    Alexandre Dmitriev

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Svedendahl, M., Chen, S., Käll, M. (2012). An Introduction to Plasmonic Refractive Index Sensing. In: Dmitriev, A. (eds) Nanoplasmonic Sensors. Integrated Analytical Systems. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3933-2_1

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