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Phenotypic Markers in Event-Related Potentials

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Neurophenotypes

Part of the book series: Innovations in Cognitive Neuroscience ((Innovations Cogn.Neuroscience))

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Abstract

Event-related brain potentials (ERPs) are a noninvasive method of measuring brain activity during cognitive processing. ERPs provide an insight into very early stages of information processing. Because of their high temporal resolution, noninvasiveness, relatively low cost, and ability to provide a continuous measure of the brain’s information processing, ERPs have been widely adopted by scientists to study normal cognitive processing and functions at different developmental stages, as well as to illuminate how and why these cognitive processes are altered in neurological and psychiatric disorders. A number of ERPs have been identified as intermediate markers or endophenotypes for psychiatric illnesses. This chapter selectively describes six ERP measures that are commonly studied in neuropsychiatric disorders. Each measure may be useful in diagnosis prediction, identifying genetic susceptibility, understanding cognitive behavior and brain function, and as biomarkers for drug discovery.

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Authors and Affiliations

  1. Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, USA

    Mei Hua-Hall

  2. Department of Psychiatry, Harvard Medical School, Boston, USA

    Mei Hua-Hall

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Correspondence to Mei Hua-Hall .

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Editors and Affiliations

  1. Communication science & Disorders/Behavioral Neuroscience , Emerson College; Boston University school of Medicine, BOSTON, Massachusetts, USA

    Vinoth Jagaroo

  2. Marine medical centre and Marine Medical Research, Chan School of Public Health , Tufts University School of medicine and Harvard TH, BOSTON, Massachusetts, USA

    Susan L. Santangelo

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Hua-Hall, M. (2016). Phenotypic Markers in Event-Related Potentials. In: Jagaroo, V., Santangelo, S. (eds) Neurophenotypes. Innovations in Cognitive Neuroscience. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-3846-5_13

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