Abstract
Understanding the specific changes that occurl in the DNA, RNA, and proteins of cancerous cells may allow for the identification of markers for early cancer detection, prevention and in the development of molecular-targeted treatments. Gene expression profiling is a powerful tool that allows for the evaluation of thousands of genes simultaneously and can provide insight into the complex interactions between genes in biologic specimen (Fingleton, Cancer Genomics–Proteomics 4:211–221, 2007). Proteomic tools have enabled the analysis of thousands of proteins and the identification of disease-specific proteins (Hudler et al, Clinical and Experimental Metastasis 27:441–451, 2010). These tools have the potential to lead to clinical applications such as improved diagnosis, an understanding specific tumor behavior, prognosis indicators and prediction of response to different treatment modalities.
Keywords
- Cancer Gene Census
- Electrospray Ionization Mass Spectrometer
- Genome Genome
- Proteomic Pattern Analysis
- Detailed Classification Scheme
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Fausto de Souza, D. (2013). Genomics and Proteomics. In: Burnier, J., Burnier, Jr., M. (eds) Experimental and Clinical Metastasis. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3685-0_22
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