Abstract
The changes in the ECM composition induced by the invading tumor cells have been discussed in previous chapters. We now focus on the following step of the metastatic cascade, the access of malignant cells to the host’s bloodstream. The importance of understanding this early step of disease progression is crucial because most cancer patients die from metastases rather than from their primary tumors.
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Fernandes, B. (2013). Hematogenous Dissemination. In: Burnier, J., Burnier, Jr., M. (eds) Experimental and Clinical Metastasis. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3685-0_13
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