Metabolic Syndrome

  • Nanette B. Silverberg
  • Nanette B. Silverberg
Chapter

Abstract

With the rising incidence of obesity in the United States, nearly a third of US inhabitants will be at high risk for the metabolic syndrome. The metabolic syndrome is a combination of obesity, cardiovascular risk factors including elevated cholesterol and triglycerides, and diabetes mellitus. This article reviews briefly the features of the metabolic syndrome. Obesity (elevated BMI) and acanthosis nigricans should prompt evaluation for insulin resistance, irrespective of race.

Keywords

Cholesterol Obesity Triglyceride 

References

  1. 1.
    Aswani R, Lochow A, Dementieva Y, Lund VA, Elitsur Y (2011) Acanthosis nigricans as a clinical marker to detect insulin resistance in caucasian children from West Virginia. Clin Pediatr (Phila) 50(11):1057–1061CrossRefGoogle Scholar
  2. 2.
    Nguyen TT, Keil MF, Russell DL, Pathomvanich A, Uwaifo GI, Sebring NG, Reynolds JC, Yanovski JA (2001) Relation of acanthosis nigricans to hyperinsulinemia and insulin sensitivity in overweight African American and white children. J Pediatr 138(4):474–480PubMedCrossRefGoogle Scholar
  3. 3.
    Stuart CA, Pate CJ, Peters EJ (1989) Prevalence of acanthosis nigricans in an unselected population. Am J Med 87(3):269–272PubMedCrossRefGoogle Scholar
  4. 4.
    Sherry N, Hassoun A, Oberfield SE, Manibo AM, Chin D, Balachandar S, Pierorazio P, Levine LS, Fennoy I (2005) Clinical and metabolic characteristics of an obese, Dominican, pediatric population. J Pediatr Endocrinol Metab 18(11):1063–1071PubMedCrossRefGoogle Scholar
  5. 5.
    Shipman AR, Millington GW (2011) Obesity and the skin. Br J Dermatol 165:743–750PubMedCrossRefGoogle Scholar
  6. 6.
    Silverberg JI, Kleiman E, Lev-Tov H, Silverberg NB, Durkin HG, Joks R, Smith-Norowitz TA (2011) Association between obesity and atopic dermatitis in childhood: a case-control study. J Allergy Clin Immunol 127:1180–1186PubMedCrossRefGoogle Scholar
  7. 7.
    Mathur AN, Goebel L (2011) Skin findings associated with obesity. Adolesc Med State Art Rev 22:146–156, ixGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Nanette B. Silverberg
    • 1
  • Nanette B. Silverberg
    • 2
  1. 1.Columbia University College of Physicians and SurgeonsNew YorkUSA
  2. 2.Department of DermatologyPediatric and Adolescent Dermatology St. Luke’s-Roosevelt Hospital and Beth Israel Medical CentersNew YorkUSA

Personalised recommendations