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Soft Tissue-to-Bone Healing in Anterior Cruciate Ligament Reconstruction

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Structural Interfaces and Attachments in Biology

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Abstract

The anterior cruciate ligament (ACL) of the knee acts as the primary restraint to anterior translation of the tibia and is a secondary restraint to varus and valgus stress. It is estimated that 800,000 ACL tears occur annually, leading to high levels of knee instability as well as meniscal and cartilage injuries. The most common treatment for ACL tears is reconstruction with intra-articular grafts. This chapter reviews reconstruction strategies for ACL repair, with an emphasis on graft choices and repair techniques. Successful ACL reconstruction relies on incorporation of the graft into the bone tunnel. Poor healing at the interface between the graft and the bone can lead to loosening and potential failure of the reconstruction. The slow and variable outcome of current reconstruction approaches has generated strong interest in biologic, mechanical, and tissue engineering strategies for improving ACL repair.

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Authors and Affiliations

  1. Sports Medicine and Shoulder Center, Triangle Orthopaedic Associates, Durham, NC, USA

    John M. Solic

  2. Department of Orthopaedic Surgery, Sports Medicine and Shoulder Service, The Hospital for Special Surgery/Weill Cornell Medical College, 535 East 70th Street, New York, NY, 10021, USA

    Scott A. Rodeo

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  1. John M. Solic
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  2. Scott A. Rodeo
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Correspondence to Scott A. Rodeo .

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Editors and Affiliations

  1. , Department of Orthopedic Surgery, Washington University, South Euclid 660, St. Louis, 63110, Missouri, USA

    Stavros Thomopoulos

  2. , Engineering Education Center, Missouri University of Science and Tech., University Blvd. One, St. Louis, 63121, Missouri, USA

    Victor Birman

  3. , Mechanical Engineering, Washington University, 1 Brookings Drive, St. Louis, 63130, Missouri, USA

    Guy M. Genin

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Solic, J.M., Rodeo, S.A. (2013). Soft Tissue-to-Bone Healing in Anterior Cruciate Ligament Reconstruction. In: Thomopoulos, S., Birman, V., Genin, G. (eds) Structural Interfaces and Attachments in Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3317-0_13

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