Decreasing Postprandial Plasma Glucose Using an α-Glucosidase Inhibitor in Subjects with IGT for the Prevention of Type 2 Diabetes Mellitus: The STOP-NIDDM Trial

  • Jean-Louis Chiasson
  • Markku Laakso
  • Markolf Hanefeld


We are currently witnessing a worldwide explosion in the prevalence of type 2 diabetes mellitus [1]. Because of the high morbidity and the excess mortality associated with diabetes, it has major societal implications [2, 3]. Diabetes still remains the most common cause of blindness, end-stage renal disease and non-traumatic amputation and a major cause of cardiovascular disease (CVD) [4, 5]. Consequently, it has a strong impact on healthcare cost [6]. Given the magnitude of the problem, type 2 diabetes is one of the major challenges of the twenty-first century. The only way that we can curtail this ever-growing problem is by developing and implementing prevention strategies.


Metabolic Syndrome Fasting Plasma Glucose Oral Glucose Tolerance Test Impaired Glucose Tolerance Intima Media Thickness 
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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Jean-Louis Chiasson
    • 1
  • Markku Laakso
    • 2
  • Markolf Hanefeld
    • 3
  1. 1.Department of Medicine, Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM)Université de MontréalMontréalCanada
  2. 2.Department of MedicineUniversity of Eastern FinlandKuopioFinland
  3. 3.Centre for Clinical StudiesDresdenGermany

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