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Nonclassic, Extraskeletal Manifestations of Primary Hyperparathyroidism

Associated Symptoms and Possible Mechanisms

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Handbook of Parathyroid Diseases

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Abstract

Historically, patients with PHPT presented with manifestations of hypercalcemia, such as kidney stones, overt bone disease, and neuromuscular dysfunction. Today, patients are often diagnosed with PHPT in the course of routine biochemical screening and frequently have vague, nonspecific symptoms. Recognizing the changing presentation of PHPT, the NIH convened two consensus conferences to determine which subset of patients with PHPT might be safely observed and have their disease medically managed and which patients would benefit from operative intervention.

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Authors and Affiliations

  1. Department of Surgical Oncology, Unit 1484, The University of Texas M. D. Anderson Cancer Center, 1400 Pressler Street Boulevard, Houston, TX, 77030, USA

    Nancy D. Perrier MD, FACS & Storm Weaver

  2. Human Neuroimaging Laboratory, Baylor College of Medicine, Houston, TX, USA

    Swaroop Gantela MD

  3. Bone & Mineral Metabolism, Bone & Mineral Research Laboratory, Henry Ford Medical Center, New Center One, Henry Ford Hospital, Suite 800, 3031 W. Grand Blvd., Detroit, MI, 48202, USA

    D. Sudhaker Rao MBBS, FACP, FACE

Authors
  1. Nancy D. Perrier MD, FACS
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  2. Storm Weaver
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  3. Swaroop Gantela MD
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  4. D. Sudhaker Rao MBBS, FACP, FACE
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Corresponding author

Correspondence to Nancy D. Perrier MD, FACS .

Editor information

Editors and Affiliations

  1. , Dept of Endocrinology and Metabolism, McMaster University, [not given], Hamilton, L8S4L8, Ontario, Canada

    Aliya A. Khan, MD

  2. Mt. Zion Medical Center, Dept. Surgery, University of California, San Francisco, Divisadero St. 1600, San Francisco, 94115, California, USA

    Orlo H. Clark

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© 2012 Springer Science+Business Media, LLC

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Perrier, N.D., Weaver, S., Gantela, S., Rao, D.S. (2012). Nonclassic, Extraskeletal Manifestations of Primary Hyperparathyroidism. In: Khan, MD, A., Clark, O. (eds) Handbook of Parathyroid Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-2164-1_8

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  • DOI: https://doi.org/10.1007/978-1-4614-2164-1_8

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  • Online ISBN: 978-1-4614-2164-1

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