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Local Environmental Control Technique for Bacterial Flagellar Motor

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Nanorobotics

Abstract

Micro/nanorobots have attracted scientific attention to develop novel technologies such as drug delivery systems. Recently, microorganisms, especially flagellated bacteria, have been used as propulsion for microobjects. To enhance the controllability of bacteria-driven microrobots, it is needed to establish a method to control the bacterial driving force directly. In many cases, the bacterial movements are regulated by the environment. Therefore, local environmental control technique is desired for bacterial driving force control. In this chapter, we introduce a local environmental control technique based on nano/micro dual pipettes for bacterial flagellar motor control. We show transient-state control of Na+-driven flagellar motor rotational speed by switching local discharges between Na+-containing and -free solutions, and steady-state control by simultaneous local discharges of the solutions with controlling discharge velocities independently. We found that rotational torque generated by the flagellar motor could be controlled in 102 pN·nm orders using the local environmental control technique based on nano/micro dual pipettes.

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Author information

Authors and Affiliations

  1. Department of Micro-Nano Systems Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan

    Toshio Fukuda & Kousuke Nogawa

  2. Center For Micro-nano Mechatronics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan

    Toshio Fukuda & Masahiro Nakajima

  3. Institute for Advanced Research, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan

    Kousuke Nogawa

  4. Department of Systems Innovation, Osaka University, 1-3, Machikaneyama-cho, Toyonaka, 560-8531, Osaka, Japan

    Masaru Kojima

  5. Division of Biological Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602, Japan

    Michio Homma

Authors
  1. Toshio Fukuda
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  2. Kousuke Nogawa
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  3. Masaru Kojima
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  4. Masahiro Nakajima
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  5. Michio Homma
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Corresponding author

Correspondence to Toshio Fukuda .

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Editors and Affiliations

  1. , Dept. of Mechanical and Industrial Eng., Northeastern University, Huntington Avenue 360, Boston, 02115, USA

    Constantinos Mavroidis

  2. ENSI Bourges, Institut PRISME, 88 Boulevard Lahitolle, Bourges, 18000, France

    Antoine Ferreira

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Fukuda, T., Nogawa, K., Kojima, M., Nakajima, M., Homma, M. (2013). Local Environmental Control Technique for Bacterial Flagellar Motor. In: Mavroidis, C., Ferreira, A. (eds) Nanorobotics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-2119-1_20

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  • DOI: https://doi.org/10.1007/978-1-4614-2119-1_20

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-2118-4

  • Online ISBN: 978-1-4614-2119-1

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