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Principles of 1H NMR Spectroscopy In Vivo

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Neural Metabolism In Vivo

Part of the book series: Advances in Neurobiology ((NEUROBIOL,volume 4))

Abstract

This chapter gives a brief overview of the principles of 1H NMR spectroscopy when applied to study metabolism in vivo. The basic methodology of in vivo 1H NMR, such as spatial localization, shimming and water suppression is described. Special attention is given to spectral quantification. The problem of spectral overlap of resonances is addressed through the use of spectral editing methods.

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Authors and Affiliations

  1. Departments of Diagnostic Radiology and Biomedical Engineering, Magnetic Resonance Research Center, School of Medicine, Yale University, TAC, N145, 300 Cedar Street, 208043, New Haven, CT, 06520-8043, USA

    Robin A. de Graaf Ph.D.

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  1. Robin A. de Graaf Ph.D.
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Correspondence to Robin A. de Graaf Ph.D. .

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Editors and Affiliations

  1. School of Medicine, Hoglund Brain Imaging Center, University of Kansas, Rainbow Blvd. 3901, Kansas City, 66160, Kansas, USA

    In-Young Choi

  2. Inst. Physique de la Matière Complexe, Labo. d'Imagerie Fonctionnelle et, Ecole Polytechnique Fédérale de Lausanne, Lausanne, 1015, Switzerland

    Rolf Gruetter

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de Graaf, R.A. (2012). Principles of 1H NMR Spectroscopy In Vivo . In: Choi, IY., Gruetter, R. (eds) Neural Metabolism In Vivo. Advances in Neurobiology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-1788-0_5

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