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Neural Metabolism In Vivo pp 305–329Cite as

Neuroreceptor Imaging

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Part of the book series: Advances in Neurobiology ((NEUROBIOL,volume 4))

Abstract

Neuroreceptor imaging using PET and SPECT has contributed to clinical neuroscience and diagnosis (e.g. neurodegenerative disease and antipsychotic-drug receptor occupancy). Recent advances in dedicated PET and SPECT instrumentation, disease-specific radioligands, and image analysis techniques contributed to the further development of this field and its widespread application. In this chapter, we introduce the basis concepts of neuroreceptor imaging using typical radioligands, standard modeling and analysis techniques and discuss future research opportunities in the field.

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Acknowledgements

This work was supported by the Swiss National Science Foundation under grants SNSF 31003A-135576 and SNSF 33CM30-124114.

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Authors and Affiliations

  1. Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland

    Habib Zaidi Ph.D.

  2. Geneva Neuroscience Center, Geneva University, Geneva, Switzerland

    Habib Zaidi Ph.D.

  3. Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

    Habib Zaidi Ph.D.

  4. Division of Medical Physics, Tohoku University Graduate School of Medicine, Sendai, Japan

    Miho Shidahara Ph.D.

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  1. Habib Zaidi Ph.D.
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Correspondence to Habib Zaidi Ph.D. .

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Editors and Affiliations

  1. School of Medicine, Hoglund Brain Imaging Center, University of Kansas, Rainbow Blvd. 3901, Kansas City, 66160, Kansas, USA

    In-Young Choi

  2. Inst. Physique de la Matière Complexe, Labo. d'Imagerie Fonctionnelle et, Ecole Polytechnique Fédérale de Lausanne, Lausanne, 1015, Switzerland

    Rolf Gruetter

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Zaidi, H., Shidahara, M. (2012). Neuroreceptor Imaging. In: Choi, IY., Gruetter, R. (eds) Neural Metabolism In Vivo. Advances in Neurobiology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-1788-0_11

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