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Bead-based arrays: multiplex analyses

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Green Technologies in Food Production and Processing

Part of the book series: Food Engineering Series ((FSES))

Abstract

The increased demand for analytical methods to detect and quantify a large number of biomolecules in small volumes of samples has led to the development of multiplexed molecular analysis. This recent technology combines the use of encoded microspheres, coupling molecules, and flow cytometry to analyze the presence of multiple compounds in a sample. It is a powerful technique that can potentially discriminate up to 100 different analytes in a single sample. Benefits include its high sensitivity and accuracy, low cost per analysis, and short time of analysis. When coupled with its multiplexing capacity, it could be classified as a promising green technology in research. The technique has found applications in biological fields where it is used to perform immunoassays and deoxyribonucleic acid (DNA) sequence analysis. Recent applications in food quality include the detection of toxins, allergens, pathogens, and antibiotics. Future developments of this promising technique are yet to come.

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Maltais, A., Boye, J.I. (2012). Bead-based arrays: multiplex analyses. In: Boye, J., Arcand, Y. (eds) Green Technologies in Food Production and Processing. Food Engineering Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-1587-9_18

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