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Opioid Adverse Effects and Opioid-Induced Hypogonadism

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Book cover Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches

Abstract

Opioids are potent pain relievers and have been used as analgesics for centuries. Unfortunately, adverse effects related to opioids may result in discontinuation of these medications and other potentially worse outcomes. An understanding of the major adverse effects of opioids as well as knowledge of how to evaluate and manage these adverse effects will improve a physician’s ability to successfully treat patients requiring opioids. In this chapter, we will review opioid-related nausea and vomiting, constipation, neuroendocrine effects, immune effects, respiratory depression, central nervous system effects, and pruritis.

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Authors and Affiliations

  1. Rehabilitation & Pain Specialists, 107 Gamma Drive, Suite 220, Pittsburgh, PA, 15238, USA

    Saloni Sharma B.A., M.D.

  2. Department of Anesthesiology, Pennsylvania State University College of Medicine, 500 University Blvd, Hershey, PA, 17033, USA

    David M. Giampetro M.D.

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  1. Saloni Sharma B.A., M.D.
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  2. David M. Giampetro M.D.
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Correspondence to Saloni Sharma B.A., M.D. .

Editor information

Editors and Affiliations

  1. The Center for Pain Relief, Inc., West Virginia University, 400 Court Street, Suite 100, Charleston, 25301, West Virginia, USA

    Timothy R. Deer

  2. Stanford Pain Management Center, Redwood City, CA, Clinic Chief, Stanford University School of Medicine, Stanford, 94065, California, USA

    Michael S. Leong

  3. Department of Anesthesiology, Rush Medical College, Professor, Rush University Medical Center, Chicago, 60612, Illinois, USA

    Asokumar Buvanendran

  4. Pennsylvania State University, College of Medicine, Department of Anesthesiology, Milton S. Hershey Medical Center, Hershey, 17033-0850, Pennsylvania, USA

    Vitaly Gordin

  5. Center for Interventional Pain and Spine, Newark, DE USA, Medical Director, Bryn Mawr Hospital, Bryn Mawr, 19010, Pennsylvania, USA

    Philip S. Kim

  6. President, National Institute of Pain, Tampa, 33558, Florida, USA

    Sunil J. Panchal

  7. The LITE Center, Clinical Associate Professor, Medical Director, School of Medicine, Miami, 33143, Florida, USA

    Albert L. Ray

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© 2013 American Academy of Pain Medicine

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Sharma, S., Giampetro, D.M. (2013). Opioid Adverse Effects and Opioid-Induced Hypogonadism. In: Deer, T., et al. Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1560-2_11

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