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Endothelium Biology

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Coronary Heart Disease

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Abstract

The endothelium lines the blood vessels of arteries, veins, and lymphatics. In the cardiovascular system, it plays a vital role in multiple functions ranging from control of vascular tone to repair after injury. This chapter focuses on endothelium biology, specifically that of the coronary tree, and its translational implications. It describes how the endothelium becomes dysfunctional during coronary artery disease and how this dysfunction can be measured and treated.

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  1. Department of Medicine, University of Alberta Hospital, Edmonton, AB, Canada

    Michael Sean McMurtry BASc, MD, PhD & Evangelos D. Michelakis MD, PhD

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    Daniel J. Garry

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McMurtry, M.S., Michelakis, E.D. (2012). Endothelium Biology. In: Vlodaver, Z., Wilson, R., Garry, D. (eds) Coronary Heart Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-1475-9_11

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