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Lipid Rafts, Caveolae and GPI-Linked Proteins

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Caveolins and Caveolae

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 729))

Abstract

Lipid rafts and caveolae are specialized membrane microdomains enriched in sphingolipids and cholesterol. They function in a variety of cellular processes including but not limited to endocytosis, transcytosis, signal transduction and receptor recycling. Here, we outline the similarities and differences between lipid rafts and caveolae as well as discuss important components and functions of each.

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Authors and Affiliations

  1. Kentucky Pediatric Research Institute, University of Kentucky, Lexington, Kentucky, USA

    Valerie L. Reeves, Candice M. Thomas & Eric J. Smart

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  1. Valerie L. Reeves
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  2. Candice M. Thomas
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  3. Eric J. Smart
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Correspondence to Eric J. Smart .

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Editors and Affiliations

  1. Department of Stem Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    Jean-François Jasmin PhD

  2. Departments of Cancer Biology, and Stem Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    Philippe G. Frank PhD  & Michael P. Lisanti MD, PhD  & 

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Reeves, V.L., Thomas, C.M., Smart, E.J. (2012). Lipid Rafts, Caveolae and GPI-Linked Proteins. In: Jasmin, JF., Frank, P.G., Lisanti, M.P. (eds) Caveolins and Caveolae. Advances in Experimental Medicine and Biology, vol 729. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1222-9_1

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