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The Indwelling Bladder Catheter: Attempts to Prevent Infection and the Development of Bacterial Biofilms

  • David SticklerEmail author
  • Roger Feneley
Chapter

Abstract

The Foley indwelling bladder catheter is the most commonly deployed prosthetic medical device. While this catheter provides a convenient way to drain urine from the bladder, it also provides easy access to the bladder for bacteria contaminating the skin insertion site. In addition the catheter undermines the basic antibacterial defenses within the lower urinary tract. As a result, catheter-associated urinary tract infections are the most common infections acquired by patients in healthcare facilities. Bacterial biofilms form readily on these catheters and play important roles in the pathogenesis of the conditions that complicate the care and seriously threaten the health of catheterized patients. This chapter reviews the many attempts that have been made to prevent infection and biofilm formation by incorporating antimicrobial agents such as silver, nitrofurazone, minocycline, rifampicin, other antibiotics and biocides into catheters. The failure of antimicrobial catheters to prevent the development of the particularly troublesome crystalline biofilms is discussed and the need explained for fundamental changes in the design of catheters.

Keywords

Foley Catheter Asymptomatic Bacteriuria Oleyl Alcohol Silicone Catheter Catheter Surface 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Darouiche RO. Device-associated infections: a macroproblem that starts with microadherence. Clin Infect Dis. 2001;33:1567–72.CrossRefGoogle Scholar
  2. 2.
    Jepsen OB, Larsen SO, Dankert J, et al. Urinary tract infection and bacteraemia in hospitalized medical patients—a European multicentre prevalence survey on nosocomial infection. J Hosp Infect. 1982;3:241–52.CrossRefGoogle Scholar
  3. 3.
    Warren JW, Steinberg L, Hebel JR, Tenney JH. The prevalence of urethral catheterization in Maryland nursing homes. Arch Intern Med. 1989;149:1535–7.CrossRefGoogle Scholar
  4. 4.
    Zimakoff J, Pontoppidan B, Larsen SO, Stickler DJ. Management of urinary bladder function in Danish hospitals, nursing homes and home care. J Hosp Infect. 1993;24:183–99.CrossRefGoogle Scholar
  5. 5.
    Sørbye LW, Finne-Soveri H, Ljunggren G, Topinkova E, Bernabei R. Indwelling catheter use in home care: elderly aged +65 in 11 different countries in Europe. Age Ageing. 2005;34:377–81.CrossRefGoogle Scholar
  6. 6.
    Beeson P. The case against the catheter. Am J Med. 1958;24:1–3.CrossRefGoogle Scholar
  7. 7.
    Hendlin K, Meyers J, Monga M. Foley catheter characteristics: predicting problems. J Endourol. 2009;23:169–71s.CrossRefGoogle Scholar
  8. 8.
    Tan GW, Chan SP, Ho CK. Is transurethral catheterization the ideal method of bladder drainage? A survey of patient satisfaction with indwelling transurethral urinary catheters. Asian J Surg. 2010;33:31–6.CrossRefGoogle Scholar
  9. 9.
    Niel-Weise BS, van den Broek PJ. Urinary catheter policies for short-term bladder drainage in adults. Cochrane Database Sys Revs. 2005;3:1–39.Google Scholar
  10. 10.
    Tenke P, Kovacs B, Bjerklund, Johansen T, Matsumoto T. European and Asian guidelines on the management and prevention of catheter-associated urinary tract infections. Int J Antimicrob Agents. 2008; 31 Suppl 1:S68–S78.Google Scholar
  11. 11.
    Stamm WE. Catheter-associated urinary tract infections: epidemiology, pathogenesis and prevention. Am J Med. 1991;91(Suppl 3B):65s–71s.CrossRefGoogle Scholar
  12. 12.
    Kunin CM, Douthitt S, Dancing J, Anderson J, Moeschberger M. The association between the use of urinary catheters and morbidity and mortality among elderly patients in nursing homes. Am J Epidemiol. 1992;135:291–301.Google Scholar
  13. 13.
    Krieger JN, Kaiser DL, Wenzel RP. Urinary tract etiology of bloodstream infections in hospitalized patients. J Infect Dis. 1983;148:57–62.CrossRefGoogle Scholar
  14. 14.
    Bryan CS, Reynolds KL. Hospital-acquired bacteremic urinary tract infection: epidemiology and outcome. J Urol. 1984;132:484–98.Google Scholar
  15. 15.
    Saint SJ. Clinical and economic consequences of nosocomial catheter-related bacteriuria. Am J Infect Control. 2000;28:68–75.CrossRefGoogle Scholar
  16. 16.
    Kunin CM. Care of the urinary catheter. In: Kunin CM, editor. Detection, prevention and management of urinary tract infections. 5th ed. Baltimore: Williams and Wilkins; 1997. p. 226–78.Google Scholar
  17. 17.
    Clayton CL, Chawla JC, Stickler DJ. Some observations on urinary tract infections in patients undergoing long-term bladder catheterization. J Hosp Infect. 1982;3:39–47.CrossRefGoogle Scholar
  18. 18.
    Maki DG, Tambyah PA. Engineering out the risk for infection with urinary catheters. Emerging Infect Dis. 2001;7:342–7.CrossRefGoogle Scholar
  19. 19.
    Meers PD, Ayliffe GAJ, Emmerson AM, Leigh DA, Mayon-White RT, Mackintosh CA et al. National survey of infections in hospitals 1980. Part 2, Urinary tract infection. J Hosp Infect. 1981;Suppl 2:23–28.Google Scholar
  20. 20.
    Hayley RW, Culver DH, White JW, Morgan WM, Emori TG. The nationwide nosocomial infection rate. Am J Epidemiol. 1985;121:159–67.Google Scholar
  21. 21.
    Tambyah PA, Halvorson KT, Maki DG. A prospective study of pathogenesis of catheter-associated urinary tract infections. Mayo Clin Proc. 1999;74:131–6.CrossRefGoogle Scholar
  22. 22.
    Matsukawa M, Kunishima Y, Takahashi S, Takeyama K, Tsukamoto T. Bacterial colonization on intraluminal surface of urethral catheters. Urology. 2005;65:440–4.CrossRefGoogle Scholar
  23. 23.
    Warren JW, Tenney JH, Hoopes JM, Muncie HL, Anthony WC. A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters. J Infect Dis. 1982; 146:719–23.CrossRefGoogle Scholar
  24. 24.
    Ohkawa M, Sugata T, Sawaki M, Nakashima T, Fuse H, Hisazumi H. Bacterial and crystal adherence to the surfaces of indwelling urethral catheters. J Urol. 1990;143:717–21.Google Scholar
  25. 25.
    Stickler DJ. Bacterial biofilms and catheter-associated urinary tract infection. Nature Clin Prac Urol. 2008;5:598–608.CrossRefGoogle Scholar
  26. 26.
    Stickler DJ, Zimakoff J. Complications of urinary tract infections associated with devices used for long-term bladder management. J Hosp Infect. 1994;28:177–94.CrossRefGoogle Scholar
  27. 27.
    Dance DA, Pearson AD, Seal DV, Lowes JA. A hospital outbreak caused by a chlorhexidine and antibiotic resistant Proteus mirabilis. J Hosp Infect. 1987;10:10–6.CrossRefGoogle Scholar
  28. 28.
    Butler HK, Kunin CM. Evaluation of polymyxin catheter lubricant and impregnated catheters. J Urol. 1968;100:560–6.Google Scholar
  29. 29.
    Guggenbichler JP, Boswald M, Lugauer S, Krall T. A new technology of microdispersed silver in polyurethane induces antimicrobial activity in central venous catheters. Infection. 1999;27 Suppl 1:s16–23.CrossRefGoogle Scholar
  30. 30.
    Kunin CM, Steele C. Culture of the surfaces of urinary catheters to sample urethral flora and study the effect of antibacterial therapy. J Clin Microbiol. 1985;21:902–8.Google Scholar
  31. 31.
    Fawcett C, Chawla JC, Quoraishi A, Stickler DJ. A study of the skin flora of spinal cord injured patients. J Hosp Infect. 1986;8:149–58.CrossRefGoogle Scholar
  32. 32.
    Danese PN. Antibiotic approaches: prevention of catheter colonization. Chem Biol. 2002;9: 873–80.CrossRefGoogle Scholar
  33. 33.
    Knudsen BE, Chew BH, Denstedt JD. Drug-eluting biomaterials in urology: the time is ripe. Brit J Urol Int. 2005;95:726–7.CrossRefGoogle Scholar
  34. 34.
    Santin M, Motta A, Denyer SP, Cannas M. Effect of the urine conditioning film on ureteral stent encrustation and characterization of its protein composition. Biomaterials. 1999;20:1245–51.CrossRefGoogle Scholar
  35. 35.
    Stickler DJ. Biomaterials to prevent nosocomial infections: is silver the gold standard? Curr Opin Infect Dis. 2000;13:389–93.CrossRefGoogle Scholar
  36. 36.
    Russell AD, Hugo WB. Antimicrobial activity and mechanism of action of silver. Prog Med Chem. 1994;39:351–70.CrossRefGoogle Scholar
  37. 37.
    Darouiche RO. Anti-infective efficacy of silver-coated medical prostheses. Clin Infect Dis. 1999;29:1371–7.CrossRefGoogle Scholar
  38. 38.
    Schierholz JM, Yücel N, Rump AF, Beuth J, Pulverer G. Anti-infective and encrustation-inhibiting materials: myths and facts. Int J Antimicrobial Ag. 2002;19:511–6.CrossRefGoogle Scholar
  39. 39.
    Kumon H, Hashimoto H, Nishimura M, Monden K, Ono N. Catheter-associated urinary tract infections: impact of catheter materials on their management. Int J Antimicrob Ag. 2001;17:311–6.CrossRefGoogle Scholar
  40. 40.
    Samuel U, Guggenbichler JP. Prevention of catheter-related infections: the potential of a new nano-silver impregnated catheter. Int J Antimicrob Ag. 2004;23 Suppl 1:S75–8.CrossRefGoogle Scholar
  41. 41.
    Davis CP, Anderson MD, Hoskins S, Warren MM. Electrode and bacterial survival with iontophoresis in synthetic urine. J Urol. 1992;147:1310–3.Google Scholar
  42. 42.
    Chakravati A, Gangodawila S, Long ML, Morris NS, Blacklock AR, Stickler DJ. An electrified catheter to resist encrustation by Proteus mirabilis biofilm. J Urol. 2005;174:1129–32.CrossRefGoogle Scholar
  43. 43.
    Johnson JR, Roberts PL, Olsen RJ, Moyer KL, Stamm WE. Prevention of catheter-associated urinary tract infection with a silver oxide urinary catheter: clinical and microbiologic correlates. J Infect Dis. 1990;162:1145–50.CrossRefGoogle Scholar
  44. 44.
    Riley DK, Classen DC, Stevens LE, Burke JP. A large randomized clinical trial of a silver-impregnated catheter: lack of efficacy and staphylococcal superinfection. Am J Med. 1995;98:349–56.CrossRefGoogle Scholar
  45. 45.
    Davenport K, Keeley FX. Evidence for the use of silver alloy-coated urethral catheters. J Hosp Infect. 2005;60:298–303.CrossRefGoogle Scholar
  46. 46.
    Lundeberg T. Prevention of catheter-associated urinary tract infections by the use of silver-impregnated catheters. Lancet. 1986;2:1031.CrossRefGoogle Scholar
  47. 47.
    Leidberg H, Lundeberg T. Silver alloy-coated catheters reduce-catheter-associated bacteriuria. Br J Urol. 1990;65:379–81.CrossRefGoogle Scholar
  48. 48.
    Leidberg H, Lundeberg EP. Refinements in the coating of urethral catheters reduces the incidence of catheter-associated bacteriuria. Eur Urol. 1990;17:236–40.Google Scholar
  49. 49.
    Verleyen P, De Ridder D, Van Poppel H, Baert L. Clinical applications of the Bardex IC Foley catheter. Eur Urol. 1999;36:240–6.CrossRefGoogle Scholar
  50. 50.
    Karchmer TB, Giannetta ET, Muto CA, Strain BA, Farr BM. A randomized cross-over study of silver-coated urinary catheters in hospitalized patients. Arch Int Med. 2000;160:3294–8.CrossRefGoogle Scholar
  51. 51.
    Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections. Am J Infect Control. 1988;16:128–40.CrossRefGoogle Scholar
  52. 52.
    Thibon P, Le Coutour X, Leroyer R, Fabry J. Randomized multi-centre trial of the effects of a catheter coated with hydrogel and silver salts on the incidence of hospital-acquired urinary tract infection. J Hosp Infect. 2000;45:117–24.CrossRefGoogle Scholar
  53. 53.
    Saint SJ, Elmore JG, Sullivan SD, Emerson SS, Koepsell TD. The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis. Am J Med. 1988;105:236–41.CrossRefGoogle Scholar
  54. 54.
    Niel-Weise BS, Arend SM, van den Broek PJ. Is there evidence for recommending silver-coated urinary catheters in guidelines? J Hosp Infect. 2002;52:81–7.CrossRefGoogle Scholar
  55. 55.
    Lai KK, Fontecchio SA. Use of silver hydrogel urinary catheters on incidence of catheter-­associated urinary tract infections in hospitalized patients. Am J Infect Control. 2002;30:221–5.CrossRefGoogle Scholar
  56. 56.
    Rupp ME, Fitzgerald T, Marion N, et al. Effect of silver-coated urinary catheters: efficacy, cost effectiveness and antimicrobial resistance. Am J Infect Control. 2004;32:445–50.CrossRefGoogle Scholar
  57. 57.
    Srinivasan A, Karchmer T, Richards A, Song X, Perl TM. A prospective trial of a novel ­silicone-based silver-coated Foley catheters for the prevention of nosocomial urinary tract infections. Infect Control Hosp Epidemiol. 2006;27:38–43.CrossRefGoogle Scholar
  58. 58.
    Crnish CJ, Drinka PJ. Does the composition of urinary catheters influence clinical outcomes and the results of research studies? Infect Control Hosp Epidemiol. 2007;28:102–3.CrossRefGoogle Scholar
  59. 59.
    Lambert HP, O’Grady FW. Antibiotic and chemotherapy. 6th ed. Edinburgh: Churchill Livingstone; 1992.Google Scholar
  60. 60.
    Johnson JR, Berggren T, Conway AJ. Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens. Antimicrob Ag Chemother. 1993;37:2033–6.CrossRefGoogle Scholar
  61. 61.
    Johnson JR, Delavari P, Azar M. Activities of a nitrofurazone containing catheter and a silver hydrogel catheter against multi-drug resistant bacteria characteristic of catheter-associated urinary tract infection. Antimicrobial Ag Chemother. 1999;43:2990–5.Google Scholar
  62. 62.
    Lee SM, Short TD, Unsworth A. Design and development of a novel automatic valve system for long-term catheterized urinary incontinence patients. Proc Inst Mech Eng [H]. 2007;221:665–75.CrossRefGoogle Scholar
  63. 63.
    Johnson JR, Kuskowski MA, Wilt TJ. Systematic review: antimicrobial urinary catheters to prevent catheter-associated urinary tract infection in hospitalized patients. Ann Int Med. 2006; 144:116–26.Google Scholar
  64. 64.
    Maki DG, Knasinski V, Tambyah PA. A prospective investigatory blinded trial of a novel nitrofurazone-impregnated urinary catheter. Infect Control Hosp Epidemiol. 1997;18:P50.Google Scholar
  65. 65.
    Al-Habdan I, Sadat-Ali M, Corea JR, Al-Othman A, Kamal BA, Shriyan DS. Assessment of nosocomial urinary tract infections in orthopaedic patients: a prospective and comparative study using two different catheters’. Int Surg. 2003;88:152–4.Google Scholar
  66. 66.
    Stensballe J, Tvede M, Looms D, et al. Infection risk with nitrofurazone-impregnated urinary catheters in trauma patients. Ann Int Med. 2007;147:285–93.Google Scholar
  67. 67.
    Darouiche RO, Hampel TB, Boone TB, Raad II. Antimicrobial activity and durability of a novel antimicrobial-impregnated bladder catheter. Int J Antimicrob Ag. 1997;8:243–7.CrossRefGoogle Scholar
  68. 68.
    Darouiche RO, Safar H, Raad II. In vitro efficacy of antimicrobial-coated bladder catheters in inhibiting bacterial migration along catheter surface. J Infect Dis. 1997;176:1109–12.CrossRefGoogle Scholar
  69. 69.
    Darouiche RO, Smith JA, Hanna H, et al. Efficacy of antimicrobial-impregnated bladder catheters in reducing catheter-associated bacteriuria: a prospective, randomized multi-center clinical trial. Urology. 1999;54:976–81.CrossRefGoogle Scholar
  70. 70.
    Brosnahan J, Jull A, Tracey C. Types of urethral catheters for management of short-term voiding problems in hospitalized adults’. Cochrane Database Syst Rev. 2004;1:1–29.Google Scholar
  71. 71.
    Trautner BW, Hull RA, Darouiche RO. Prevention of catheter-associated urinary tract infection. Curr Opin Infect Dis. 2005;18:37–41.CrossRefGoogle Scholar
  72. 72.
    Galloway A, Green HT, Windsor JJ, Menon KK, Gardner BD. Serial concentrations of C-reactive protein as an indicator of urinary tract infection in patients with spinal injury. J Clin Path. 1986;39:851–5.CrossRefGoogle Scholar
  73. 73.
    Nicolle LE. Catheter-related urinary tract infection. Drugs Ageing. 2005;22:627–39.CrossRefGoogle Scholar
  74. 74.
    Orr PH, Nicolle LE, Duckworth H, et al. Febrile urinary tract infection in the institutionalized elderly. Am J Med. 1996;100:71–7.CrossRefGoogle Scholar
  75. 75.
    Tambyah PA, Maki DG. Catheter-associated urinary tract infection is rarely symptomatic: a prospective study of 1497 catheterized patients. Arch Intern Med. 2000;160:678–82.CrossRefGoogle Scholar
  76. 76.
    Pratt RJ, Pellowe CM, Wilson JA, et al. Epic2: National evidence-based guidelines for preventing healthcare-associated infections in NHS hospitals in England. J Hosp Infect. 2007;65 Suppl 1:S1–64.CrossRefGoogle Scholar
  77. 77.
    Hooton TM, Bradley SF, Cardenas DD, et al. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 international clinical practice guidelines from the Infectious Diseases Society of America. Clin Infect Dis. 2010;50:625–63.CrossRefGoogle Scholar
  78. 78.
    Schumm K, Lam TB. Types of urethral catheters for management of short-term voiding problems in hospitalized patients: a short version Cochrane review. Neurourol Urodyn. 2008;27:738–46.CrossRefGoogle Scholar
  79. 79.
    Richards CL, Hoffman KC, Bernard JM, Winslow SD, Norman JC, Whalen RL. Development and characterization of an infection inhibiting urinary catheter. ASAIO J. 2003;49:449–53.Google Scholar
  80. 80.
    Mobley HTL, Warren JW. Urease-positive bacteriuria and obstruction of long-term urinary catheters. J Clin Microbiol. 1987;25:2216–7.Google Scholar
  81. 81.
    Stickler DJ. Susceptibility of antibiotic-resistant Gram-negative bacteria to biocides: a perspective from the study of catheter biofilms. J Appl Microbiol. 2002;92(suppl):163S–70.CrossRefGoogle Scholar
  82. 82.
    Gaonakar TA, Sampath LA, Modak SM. Evaluation of the antimicrobial efficacy of urinary catheters impregnated with antiseptics in an invitro urinary tract model. Infect Cont Hosp Epidemiol. 2003;24:506–13.CrossRefGoogle Scholar
  83. 83.
    Goanakar TA, Careos L, Modak SM. Efficacy of a silicone urinary catheter impregnated with chlorhexidine and triclosan against colonization with Proteus mirabilis and other urinary pathogens. Infect Control Hosp Epidemiol. 2007;28:596–8.CrossRefGoogle Scholar
  84. 84.
    Kwok CS, Horbett TA, Ratner BD. Design of infection resistant antibiotic-releasing polymers. II Controlled release of antibiotics through a plasma-deposited thin film barrier. J Control Release. 1999;62:301–11.CrossRefGoogle Scholar
  85. 85.
    Cho YH, Lee SJ, Lee JY, et al. Prophylactic efficacy of a new gentamicin-releasing urethral catheter in short-term catheterized rabbits. Br J Urol Int. 2001;87:104–9.CrossRefGoogle Scholar
  86. 86.
    Cho YW, Park JH, Kim SH, et al. Gentamicin-releasing urethral catheter for short-term catheterization. J Biomater Sci Polym Ed. 2003;14:962–72.CrossRefGoogle Scholar
  87. 87.
    Park JH, Cho YW, Cho YH, et al. Norfloxacin-releasing urethral catheter for long-term catheterization. J Biomater Sci Polym Ed. 2003;14:951–62.CrossRefGoogle Scholar
  88. 88.
    Pugnash JL, DiTizio V, Mittleman MW, Bruce AW, DiCosmo F, Khoury AE. Antibiotic hydrogel-coated Foley catheters for prevention of urinary tract infection in a rabbit model. J Urol. 1999;162:883–7.CrossRefGoogle Scholar
  89. 89.
    Maeda M, Kumano A, Tirrell DA. H+-induced release of contentsof phosphatidylcholine vesicles bearing surface-bound polyelectrolyte chains. J Am Chem Soc. 1988;110:7455–9.CrossRefGoogle Scholar
  90. 90.
    Kono K. Thermosensitive polymer-modified liposomes. Adv Drug Rev. 2001;53:307–19.CrossRefGoogle Scholar
  91. 91.
    Meers P. Enzyme-activated targeting of liposomes. Adv Drug Delivery Rev. 2001;53:265–72.CrossRefGoogle Scholar
  92. 92.
    Woo GL, Mittleman MW, Santerre JP. Synthesis and characterization of a novel biodegradable antimicrobial polymer. Biomaterials. 2000;21:1235–46.CrossRefGoogle Scholar
  93. 93.
    Tanahara M, Suzuki Y, Nishimura Y, Suzuki K, Kakimaru Y, Fukunishi Y. A novel microbial infection-responsive drug release system. J Pharm Sci. 1999;88:510–4.CrossRefGoogle Scholar
  94. 94.
    Kwok CS, Mourad PD, Crum LA, Ratner BD. Self-assembled molecular structures as ultra-sonically responsive barrier membranes for pulsatile drug delivery. J Biomed Mater Res. 2001; 57:151–64.CrossRefGoogle Scholar
  95. 95.
    Norris P, Noble M, Francolini I, et al. Ultrasonically controlled release of ciprofloxacin from self-assembled coatings on poly(2-hydroxyethyl methacrylate) hydrogels for Pseudomonas aeruginosa biofilm prevention. Antimicrob Ag Chemother. 2005;49:4272–9.CrossRefGoogle Scholar
  96. 96.
    Malcolm RK, McCullagh SD, Woolfson AD, Gorman SP, Jones DS, Cuddy J. Controlled release of a model antibacterial drug from a novel self-lubricating silicone biomaterial. J Control Rel. 2004;97:313–20.CrossRefGoogle Scholar
  97. 97.
    Darouiche RO, Mansouri MD, Gawande PV, Madhyastha S. Efficacy of combination of chlorhexidine and protamine sulphate against device-associated pathogens. J Antimicrob Chemother. 2008;61:651–7.CrossRefGoogle Scholar
  98. 98.
    Hachem R, Reitzel R, Borne A, et al. Novel antiseptic urinary catheters for prevention of urinary tract infections: correlation of in vivo and in vitro test results. Antimicrob Ag Chemother. 2009;53:5145–9.CrossRefGoogle Scholar
  99. 99.
    Regev-Shoshani G, Ko M, Miller C, Av-Gay Y. The slow release of nitric oxide from charged catheters and its effect on biofilm formation by Escherichia coli. Antimicrobial Agents Chemother. 2010;54:273–9.CrossRefGoogle Scholar
  100. 100.
    Getliffe K. The characteristics and management of patients with recurrent blockage of long-term urinary catheters. J Adv Nursing. 1994;20:140–9.CrossRefGoogle Scholar
  101. 101.
    Kohler-Ockmore J, Feneley RCL. Long-term catheterization of the bladder, prevalence and morbidity. Brit J Urol. 1996;77:347–51.CrossRefGoogle Scholar
  102. 102.
    Capewell AE, Morris SL. Audit of catheter management provided by district nurses and continence advisors. Brit J Urol. 1993;71:259–64.CrossRefGoogle Scholar
  103. 103.
    Morris NS, Stickler DJ, Winters C. Which indwelling urethral catheters resist encrustation by Proteus mirabilis biofilms? Brit J Urol. 1997;80:58–63.CrossRefGoogle Scholar
  104. 104.
    Morris NS, Stickler DJ, McLean RJ. The development of bacterial biofilms on indwelling catheters. World J Urol. 1999;17:345–50.CrossRefGoogle Scholar
  105. 105.
    Kunin CM. Blockage of urinary catheters: role of microorganisms and constituents of the urine on formation of encrustations. J Clin Epidemiol. 1989;42:835–42.CrossRefGoogle Scholar
  106. 106.
    Stickler DJ, Ganderton L, King J, Nettleton J, Morris NS. Proteus mirabilis biofilms and the encrustation of urethral catheters. Urol Res. 1993;21:407–11.CrossRefGoogle Scholar
  107. 107.
    Jones BD, Mobley HLT. Genetic and biochemical diversity of ureases of Proteus, Providencia and Morganella species isolated from urinary tract infection. Infect Immun. 1987;55:2198–203.Google Scholar
  108. 108.
    Stickler DJ, Morris N, Moreno MC, Sabbuba NA. Studies on the formation of crystalline bacterial biofilms on urethral catheters. Eur J Clin Microbial Infect Dis. 1998;17:649–52.CrossRefGoogle Scholar
  109. 109.
    Broomfield RJ, Morgan SD, Khan A, Stickler DJ. Crystalline bacterial biofilm formation on urinary catheters by urease producing urinary tract pathogens: a simple method of control. J Med Microbiol. 2009;58:1367–75.CrossRefGoogle Scholar
  110. 110.
    MacLeod SM, Stickler DJ. Species interaction in mixed community biofilm on urinary catheters. J Med Microbiol. 2007;56:1549–57.CrossRefGoogle Scholar
  111. 111.
    Donlan RM. Biofilms: microbial life on surfaces. Emerg Infect Dis. 2002;8:881–90.CrossRefGoogle Scholar
  112. 112.
    Jacobsen SM, Stickler DJ, Mobley HTL, Shirtliff ME. Complicated catheter-associated urinary tract infections due to Escherichia coli and Proteus mirabilis. Clin Microbiol Revs. 2008;21:26–59.CrossRefGoogle Scholar
  113. 113.
    Downer A, Morris NS, Feast WJ, Stickler DJ. Polymer surface properties and their effect on adhesion of Proteus mirabilis. Proc Inst Mech Eng. 2003;217:279–89.Google Scholar
  114. 114.
    Cox AJ. Comparison of catheter surface morphologies. Brit J Urol. 1990;65:55–60.CrossRefGoogle Scholar
  115. 115.
    Stickler DJ, Young R, Jones G, Sabbuba NS, Morris NS. Why are Foley catheters so vulnerable to encrustation and blockage by crystalline bacterial biofilm? Urol Res. 2003;31:306–11.CrossRefGoogle Scholar
  116. 116.
    Stickler DJ, Lear JC, Morris NS, et al. Observations on the adherence of Proteus mirabilis onto polymer surfaces. J Appl Microbiol. 2006;100:1028–33.CrossRefGoogle Scholar
  117. 117.
    Stickler DJ, Morgan SD. Observations on the development of the crystalline bacterial biofilms that encrust and block Foley catheters. J Hosp Infect. 2008;69:350–60.CrossRefGoogle Scholar
  118. 118.
    Morgan SD, Rigby D, Stickler DJ. A study of the structure of the crystalline biofilms that encrust and block silver Foley catheters. Urol Res. 2009;37:88–93.CrossRefGoogle Scholar
  119. 119.
    Hayward JA, Chapman D. Biomembrane surfaces as models for polymer design: the potential for haemocompatibility. Biomaterials. 1984;5:135–42.CrossRefGoogle Scholar
  120. 120.
    Campbell EJ, O’Byrne V, Stratford PW, et al. Biocompatible surfaces using methacroylphosphorylcholine laurylmethacrylate co-polymers. ASIO J. 1994;40:853–7.CrossRefGoogle Scholar
  121. 121.
    Ishihara K, Iwasaki Y. Reduced protein adsorption on novel phospholipids polymers. J Biomater Appl. 1998;13:111–27.Google Scholar
  122. 122.
    Andrews CS, Denyer SP, Hall B, Hanlon GW, Lloyd AW. A comparison of the use of an ATP-based bioluminescent assay and image analysis for the assessment of bacterial adhesion to standard HEMA and biomimetic soft contact lenses. Biomaterials. 2001;22:3225–33.CrossRefGoogle Scholar
  123. 123.
    Stickler DJ, Evans A, Morris NS, Hughes G. Strategies for the control of catheter encrustation. Int J Antimicrob Ag. 2002;19:499–506.CrossRefGoogle Scholar
  124. 124.
    Laube N, Kleinen L, Bradenahl J, Meissner A. Diamond-like carbon coatings on ureteral stents—a new strategy for decreasing the formation of crystalline bacterial biofilms? J Urol. 2007;177:1923–7.CrossRefGoogle Scholar
  125. 125.
    Kunin CM. Can we build a better urinary catheter? New Eng J Med. 1988;319:365–6.CrossRefGoogle Scholar
  126. 126.
    Garcia MM, Gulati S, Liepman D, Stackhouse GB, Greene K, Stoller ML. Traditional Foley drainage systems—Do they drain the bladder? J Urol. 2006;177:203–7.CrossRefGoogle Scholar
  127. 127.
    German K, Rowley P, Stone D, Kumar U, Blackford HN. A ramdomized cross-over study comparing the use of a catheter valve and a leg bag in urethrally catheterized male patients. Br J Urol. 1997;79:96–8.CrossRefGoogle Scholar
  128. 128.
    Fader M, Petterssen L, Brooks R, et al. A multi-centre comparative evaluation of catheter valves. Br J Nurs. 1997;6:359–67.Google Scholar
  129. 129.
    Addison R. Catheter valves: a special focus on the Bard Flip-Flo catheter. Br J Nurs. 1999; 8:576–80.Google Scholar
  130. 130.
    Doherty W. The Sims Portex catheter valve: an alternative to the leg bag. Br J Nurs. 1999;8: 459–62.Google Scholar
  131. 131.
    Sabbuba NA, Stickler DJ, Long MJ, Dong Z, Short TD, Feneley RJC. Does valve regulated release of urine from the bladder decrease encrustation and blockage of indwelling catheters by Proteus mirabilis biofilms? J Urol. 2005;173:262–6.CrossRefGoogle Scholar
  132. 132.
    Lee SJ, Kim SW, Cho YH, et al. A comparative multi-centre study on the incidence of catheter-associated urinary tract infection between nitrofurazone-coated and silicone catheters. Int J Antimicrobial Ag. 2004;24 Suppl 1:S65–9.CrossRefGoogle Scholar
  133. 133.
    Brocklehurst JC, Hickey DS, Davies I, Kennedy AP, Morris JA. A new urethral catheter. Br Med J. 1988;296:1691–3.CrossRefGoogle Scholar
  134. 134.
    Kunin CM, Finkelberg Z. Evaluation of an intraurethral lubricating catheter in preventing catheter-induced urinary tract infections. J Urol. 1971;106:928–30.Google Scholar
  135. 135.
    Lawrence EL, Turner IG. Kink flow and retention properties of urinary catheters part 2: novel design. J Mater Sci: Mater Med. 2006;17:153–9.CrossRefGoogle Scholar
  136. 136.
    Feneley RCL, Kunin CM, Stickler DJ. An indwelling catheter for the 21st century. Br J Urol Int. 2012;109:1746–9.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Cardiff School of BiosciencesCardiff UniversityCardiffUK
  2. 2.North Bristol NHS Trust, Southmead HospitalBristolUK

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