Skip to main content
SpringerLink
Log in

Cutaneous Manifestations of Pulmonary Disease

  • Chapter
  • First Online:
Atlas of Dermatology in Internal Medicine

Abstract

The recognition and correct elucidation of the cutaneous signs of diseases that primarily affect the pulmonary system may assist the clinician in diagnosis and estimation of prognosis. This chapter describes selected pulmonary diseases with distinctive cutaneous findings. Often times in medicine, findings on the skin may prove very helpful in exposing an underlying systemic condition. Pulmonary conditions can be particularly life threatening, and early detection and treatment may impact the course of a patient’s life. In all fields of medicine, especially internal medicine, pneumology, nephrology, pediatrics, and dermatology, physicians can enhance their clinical proficiency by better understanding the rare and common cutaneous manifestations of pulmonary diseases such as sarcoidosis, tuberculosis, Birt–Hogg–Dubé syndrome (BHDS), and cystic fibrosis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Sharma OP. Sarcoidosis: a historical perspective. Clin Dermatol. 2007;25:232–41.

    Article  PubMed  Google Scholar 

  2. Hutchison J. Case of a livid papillary psoriasis. In: Hutchison J, editor. Illustrations of clinical surgery. London: J & A Churchill; 1877. p. 42.

    Google Scholar 

  3. Rose A, Tielker M, Knox K. Hepatic, ocular, and cutaneous sarcoidosis. Clin Chest Med. 2008;29:509–24.

    Article  PubMed  Google Scholar 

  4. Boeck C. Multiple benign sarcoid of the skin. J Cutan Genitourin Dis. 1899;17:543–50.

    Google Scholar 

  5. Iannuzzi M, Rybicki B, Teirstein A. Medical progress sarcoidosis. N Engl J Med. 2007;357:2153–65.

    Article  PubMed  CAS  Google Scholar 

  6. Ali MM, Atwan AA, González ML. Cutaneous sarcoidosis: updates in the pathogenesis. Eur Acad Dermatol Venereol. 2010;24:747–55.

    Article  CAS  Google Scholar 

  7. Howard A, White CR. Non-infectious granulomas. In: Bolognia JL, Jorizzo JL, Rapini RP, et al., editors. Dermatology. Philadelphia: Elsevier; 2003. p. 1455–60.

    Google Scholar 

  8. Katta R. Cutaneous sarcoidosis: a dermatologic masquerader. Am Fam Physician. 2002;65:1581–4.

    PubMed  Google Scholar 

  9. Fernandez-Faith E, McDonnell J. Cutaneous sarcoidosis: differential diagnosis. Clin Dermatol. 2007;25:276–87.

    Article  PubMed  Google Scholar 

  10. Kannan S, Simpson GL, Sheehan DJ, et al. Giant verrucous nodules in a patient with tuberculosis. Am J Dermatopathol. 2009;31:591–3.

    Article  PubMed  Google Scholar 

  11. Judson M, Thompson B, Rabin D, et al. The diagnostic pathway to sarcoidosis. Chest. 2003;123:406–12.

    Article  PubMed  Google Scholar 

  12. Marchell R, Judson M. Chronic cutaneous lesions of sarcoidosis. Clin Dermatol. 2007;25:295–302.

    Article  PubMed  Google Scholar 

  13. Rosenberg B. Ichthyosiform sarcoidosis. Dermatology Online Journal. http://dermatology.cdlib.org Accessed 3 Nov 2008.

  14. Stedman TL. Stedman’s medical dictionary. 24th ed. Baltimore: Williams & Wilkins; 1982. p. 813.

    Google Scholar 

  15. Edmondstone W, Wilson A. Sarcoidosis in Caucasians, Blacks and Asians in London. Br J Dis Chest. 1985;79:27–36.

    Article  PubMed  CAS  Google Scholar 

  16. Yanardag H, Pamuk O, Pamuk G. Lupus pernio in sarcoidosis: clinical features and treatment outcomes of 14 patients. J Clin Rheumatol. 2003;9:72–6.

    Article  PubMed  Google Scholar 

  17. Judson M, Thompson B, Rabin D, et al. The diagnostic pathway to sarcoidosis. Chest. 2003;123(2):406–12.

    Article  PubMed  Google Scholar 

  18. Lodha S, Sanchez M, Prystowsky S. Sarcoidosis of the skin: a review for the pulmonologist. Chest. 2009;136:583–96.

    Article  PubMed  Google Scholar 

  19. English J, Patel P, Greer K. Sarcoidosis. J Am Acad Dermatol. 2001;44:725–43.

    Article  PubMed  Google Scholar 

  20. Darier J, Roussy G. Un cas de tumeurs benignes multiples (Sarcoidessouscutanées ou tuberculides nodulaires hypodermique). Ann Dermatol Syphiligr. 1904;5:144–9.

    Google Scholar 

  21. Marcoval J, Moreno A, Mana J, Peyri J. Subcutaneous sarcoidosis. Dermatol Clin. 2008;26:553–6.

    Article  PubMed  Google Scholar 

  22. Vainsencher D, Winkelmann R. Subcutaneous sarcoidosis. Arch Dermatol. 1984;120:1029–31.

    Article  Google Scholar 

  23. Mana J, Marcoval J, Graells J, et al. Cutaneous involvement in ­sarcoidosis. Relationship to systemic disease. Arch Dermatol. 1997;122:882–8.

    Article  Google Scholar 

  24. Ahmed L, Harshad S. Subcutaneous sarcoidosis: is it a specific subset of cutaneous sarcoidosis frequently associated with systemic disease? J Am Acad Dermatol. 2006;54:55–60.

    Article  PubMed  Google Scholar 

  25. Requena L, Sanchez Y. Panniculitis. Part II. Mostly lobular panniculitis. J Am Acad Dermatol. 2001;45:325–61.

    Article  PubMed  CAS  Google Scholar 

  26. Mehta V, Balachandran C, Mathew M. Scar sarcoidosis sparing a surgical scar. Dermatology Online Journal. http://dermatology.cdlib.org Accessed 10 Nov 2008.

  27. Minus H, Grimes P. Cutaneous manifestations of sarcoidosis in blacks. Cutis. 1983;32:361–3.

    PubMed  CAS  Google Scholar 

  28. Selim A, Ehrsam E, Atassi M, Khachemoune A. Scar sarcoidosis: a case report and brief review. Cutis. 2006;78:418–22.

    PubMed  Google Scholar 

  29. Ahbib S, Lachapelle J, Marot L. Sarcoidal granulomas following injections of botulic toxin A (Botox) for corrections of wrinkles. Ann Dermatol Venereol. 2006;133:43–5.

    Article  PubMed  CAS  Google Scholar 

  30. Henderson C, Lafleur L, Sontheimer R. Sarcoidal alopecia as a mimic of discoid lupus erythematous. J Am Acad Dermatol. 2008;59:143–5.

    Article  PubMed  Google Scholar 

  31. Douri R, Chawaf A, Alreface B. Cicatricial alopecia due to sarcoidosis. Dermatology Online Journal. http://dermatology.cdlib.org Accessed 10 Nov 2008.

  32. Katta R, Nelson B, Chen D, Roenigk H. Sarcoidosis of the scalp: A case series and review of the literature. J Am Acad Dermatol. 2000;42:690–2.

    Article  PubMed  CAS  Google Scholar 

  33. Cather J, Cohen P. Ichthyosiform sarcoidosis. J Am Acad Dermatol. 1999;40:862–5.

    PubMed  CAS  Google Scholar 

  34. Rosenberg B. Ichthyosiform sarcoisis. Dermatology Online Journal. http://dermatology.cdlib.org Accessed 10 Nov 2008.

  35. Patterson J, Fitzwater J. Case report. Hypopigmented sarcoidosis. J Tenn Med Assoc. 1978;71:662–4.

    PubMed  CAS  Google Scholar 

  36. Thomas RH, McKee P, Black M. Hypopigmented sarcoidosis. J R Soc Med. 1981;72:921–3.

    Google Scholar 

  37. Breathmach A. Branched cells in the epidermis: an overview. J Invest Dermatol. 1980;75:6–11.

    Article  Google Scholar 

  38. Clayton R, Breathnach A, Martin B, Feiwel M. Hypopigmented sarcoidosis in the negro. Report of eight cases with ultrastructural observations. Br J Dermatol. 1977;96:118–27.

    Article  Google Scholar 

  39. James D. Erythema nodosum. Br Med J. 1961;1:853–7.

    Article  PubMed  CAS  Google Scholar 

  40. Schwartz R, Nervi S. Erythema nodosum: a sign of systemic ­disease. Am Fam Physician. 2007;75:695–700.

    PubMed  Google Scholar 

  41. Rosell A, Garcia-Arranz G, Romero N, et al. Lupus pernio with involvement of nasal cavity and maxillary sinus. ORL J Otorhinolaryngol Relat Spec. 1998;60:236–9.

    Article  PubMed  CAS  Google Scholar 

  42. Vashisht P, Sahoo B, Khurana N, Reddy B. Cutaneous tuberculosis in children and adolescents: a clinicohistological study. J Eur Acad Dermatol Venereol. 2007;21:40–7.

    Article  PubMed  CAS  Google Scholar 

  43. Marmelzat W. Laennac and the ‘prosecutor’s wart’. Arch Dermatol. 1962;86:546–51.

    Google Scholar 

  44. Daniel TM. The history of tuberculosis. Respir Med. 2006;100:1862–70.

    Article  PubMed  Google Scholar 

  45. World Health Organization. Global tuberculosis control – ­surveillance, planning, financing. WHO report 2005. Geneva: World Health Organization; 2005. p. 1–247.

    Google Scholar 

  46. Valadas E, Antunes F. Tuberculosis, a re-emergent disease. Eur J Radiol. 2005;55:154–7.

    Article  PubMed  Google Scholar 

  47. Aaron L, Saadoun D, Calatroni I, et al. Tuberculosis in HIV-infected patients: a comprehensive review. Clin Microbiol Infect. 2004;10:388–98.

    Article  PubMed  CAS  Google Scholar 

  48. Hernandez C, Cetner A, Jordan J, et al. Tuberculosis in the age of biologic therapy. J Am Acad Dermatol. 2008;59:363–80.

    Article  PubMed  Google Scholar 

  49. Barbagallo J, Tager P, Ingleton R, et al. Cutaneous tuberculosis: diagnosis and treatment. Am J Clin Dermatol. 2002;3:319–28.

    Article  PubMed  Google Scholar 

  50. McKenna MT, McCray E, Onorato I. The epidemiology of tuberculosis among foreign-born persons in the United States, 1986 to 1993. N Engl J Med. 1995;332:1071–6.

    Article  PubMed  CAS  Google Scholar 

  51. Morrone A, Dassoni F, Pajno MC, et al. Ulcers of the face and neck in a woman with pulmonary tuberculosis: presentation of a clinical case. Rural Remote Health. 2010;10:1485.

    PubMed  CAS  Google Scholar 

  52. Kaufmann SH. New issues in tuberculosis. Ann Rheum Dis. 2004;63:50–6.

    Article  CAS  Google Scholar 

  53. American Thoracic Society. Diagnostic standards and classification of tuberculosis in adults and children. Am J Respir Crit Care Med. 2000;161:1376–95.

    Google Scholar 

  54. Harries A, Dye C. Tuberculosis. Ann Trop Med Parasitol. 2006;100:415–41.

    Article  PubMed  CAS  Google Scholar 

  55. Chesnutt MS, Prendergast TJ. Pulmonary tuberculosis. In: McPhee SJ, Papadakis MA, Tierney LM, editors. Current medical diagnosis and treatment 2007. New York: McGraw-Hill; 2007. p. 260–8.

    Google Scholar 

  56. Sahin N, Aydin NE, Senol M, et al. Longstanding skin ulcers due to Mycobacterium tuberculosis in a healthy man. Trop Biomed. 2010;27:120–4.

    PubMed  CAS  Google Scholar 

  57. Pandhi D, Reddy B, Chowdhary S, Khurana N. Cutaneous ­tuberculosis in Indian children: the importance of screening for involvement of internal organs. J Eur Acad Dermatol Venereol. 2004;18:546–51.

    Article  PubMed  CAS  Google Scholar 

  58. Yates V, Pormedero L. Cutaneous tuberculosis in Blackburn district (UK): a 15-year prospective series. Br J Dermatol. 1996;136:483–9.

    Article  Google Scholar 

  59. MacGregor R. Cutaneous tuberculosis. Clin Dermatol. 1995;13:245–55.

    Article  PubMed  CAS  Google Scholar 

  60. Sethuraman G, Ramesh V, Raman M, Sharma V. Skin tuberculosis in children: learning from India. Dermatol Clin. 2008;26:285–94.

    Article  PubMed  CAS  Google Scholar 

  61. Ranawaka RR, Abeygunasekara PH, Perera E, et al. Letter: Clinico-histopathological correlation and the treatment response of 20 patients with cutaneous tuberculosis. Dermatol Online J. 2010;16:13.

    PubMed  Google Scholar 

  62. Ara M, Pharm C, Baselga C, et al. Primary tuberculous chancre caused by Mycobacterium bovis after goring with a bull’s horn. J Am Acad Dermatol. 2000;43:535–7.

    Article  PubMed  CAS  Google Scholar 

  63. Ramesh V, Misra R, Beena K, Mukherjee A. A study of cutaneous tuberculosis in children. Pediatr Dermatol. 1999;16:262–9.

    Article  Google Scholar 

  64. Terranova M, Padovese V, Fornari U, Morrone A. Clinical and epidemiological study of cutaneous tuberculosis in Northern Ethiopia. Dermatology. 2008;217:89–93.

    Article  PubMed  Google Scholar 

  65. Ho CK, Ho MH, Chong LY. Cutaneous tuberculosis in Hong Kong: an update. Hong Kong Med J. 2006;12:272–7.

    PubMed  CAS  Google Scholar 

  66. Kumar B, Muralidhar S. Cutaneous tuberculosis: A twenty-year prospective study. Int J Tuberc Lung Dis. 1999;3:494–500.

    PubMed  CAS  Google Scholar 

  67. Lipsker D, Grosshans E. What is Lupus vulgaris in 2005? Dermatology. 2005;211:189–90.

    Article  PubMed  Google Scholar 

  68. Du Vivier A. Atlas of clinical dermatology: the skin and systemic disease. 3rd ed. Boston: Churchill Livingstone; 2002. p. 264–8,391,509–13.

    Google Scholar 

  69. Kumar B, Rai R, Kaur I, et al. Childhood cutaneous tuberculosis: a study over 25 years from northern India. Int J Dermatol. 2001;40:26–32.

    Article  PubMed  CAS  Google Scholar 

  70. Morais P, Ferreira O, Nogueira A, et al. A nodulo-ulcerative lesion on the nose. Dermatol Online J. 2010;16:11.

    Google Scholar 

  71. Tappeiner G, Wolff K. Tuberculosis and other mycobacterial infections. In: Fitzpatrick TB, Freedberg IM, Eisen AZ, Wolff K, Austen KF, editors. Dermatology in general medicine. 5th ed. New York: McGraw-Hill; 2003. p. 1933–50.

    Google Scholar 

  72. Sehgal V, Wagh S. Cutaneous tuberculosis: current concepts. Int J Dermatol. 1990;28:355–62.

    Google Scholar 

  73. Sehgal V. Cutaneous tuberculosis. Dermatol Clin. 1994;12:645–53.

    PubMed  CAS  Google Scholar 

  74. Bravo F, Gotuzzo E. Cutaneous tuberculosis. Clin Dermatol. 2007;25:173–80.

    Article  PubMed  Google Scholar 

  75. Stack R, Bickley L, Coppel I. Miliary tuberculosis presenting as skin lesions in a patient with acquired immunodeficiency syndrome. J Am Acad Dermatol. 1990;23:1031–5.

    Article  PubMed  CAS  Google Scholar 

  76. Sehgal VN, Wagh SA. Cutaneous tuberculosis. Current concepts. Int J Dermatol. 1990;29:237–52.

    Article  PubMed  CAS  Google Scholar 

  77. Erbagci S, Almila T, Nazan B, Erkilic S, Bayram A. Tuberculosis verrucosa cutis in a patient with long-standing generalized lichen planus: Improvement of lichen after antitubercular polychemotherapy. J Dermatolog Treat. 2006;17:314–8.

    Article  PubMed  Google Scholar 

  78. Sehgal V. Lichen scrofulosorum: current status. Int J Dermatol. 2005;44:521–3.

    Article  PubMed  Google Scholar 

  79. Mascaró J, Baselga E. Erythema induratum of Bazin. Dermatol Clin. 2008;26:439–45.

    Article  PubMed  Google Scholar 

  80. Hebra F. Lichen scrofulosorum. In: Fagge CH, Pye Smith PH, ­editors. Diseases of the skin. London: New Syndenham Society; 1868. p. 52.

    Google Scholar 

  81. Singal A. Lichen scrofulosorum: A prospective study of 39 patients. Int J Dermatol. 2005;44:489–93.

    Article  PubMed  Google Scholar 

  82. Kumar U, Sethuraman G, Verma P, et al. Psoriasiform type of lichen scrofulosorum. Pediatr Dermatol 2010. Dec 7.doi:10.1111/j.1525-1470.2010.01304X.

    Google Scholar 

  83. Bazin E. Leçons théoriques et cliniques sur la scrofule. 2nd ed. Paris: Delahaye; 1861.

    Google Scholar 

  84. Schneider J, Jordaan H, Geiger D, et al. Erythema induratum of Bazin. Am J Dermatopathol. 1995;17:350–6.

    PubMed  CAS  Google Scholar 

  85. Shimizu A, Takahashi A, Negishi I, et al. The close association of lymphadenitis tuberculosa and erythema induratum of Bazin in Japanese patients. Dermatology. 2003;207:426–7.

    Article  PubMed  CAS  Google Scholar 

  86. Garcia-Rodriguez J, Monteagudo-Sanchez B, Marino-Callejo A. Cutaneous tuberculosis: a 15-year descriptive study. Enferm Infect Microbiol Clin. 2008;26:205–11.

    Article  Google Scholar 

  87. Segura S, Pujol R, Trindade F, et al. Vasculitis in erythema induratum of Bazin: a histopathologic study of 101 biopsy specimens from 86 patients. J Am Acad Dermatol. 2008;59:839–51.

    Article  PubMed  Google Scholar 

  88. Heinemann C, Kaatz M, Elsner P. Erythema induratum of Bazin and Poncet’s disease–successful treatment with antitubercular drugs. Eur Acad Dermatol Venereol. 2003;17:334–6.

    Article  CAS  Google Scholar 

  89. Freidman P, Husain S, Grossman M. Nodular tuberculid in a patient with HIV. J Am Acad Dermatol. 2005;53:S154–6.

    Article  Google Scholar 

  90. Hara K, Tsuzuki T, Takagi N, et al. Nodular granulomatous phlebitis of the skin: a fourth type of tuberculid. Histopathology. 1997;30:129–34.

    Article  PubMed  CAS  Google Scholar 

  91. Motswaledi H, Schulz E. Superficial thrombophlebitic tuberculide. Inter J Dermatol. 2006;45:1337–40.

    Article  Google Scholar 

  92. Birt A, Hogg G, Dubé W. Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons. Arch Dermatol. 1977;113:1674–777.

    Article  PubMed  CAS  Google Scholar 

  93. Vincent A, Farley M, Chan E, James WD. Birt-Hogg-Dube syndrome: a review of the literature and the differential diagnosis of firm facial papules. J Am Acad Dermatol. 2003;49:698.

    Article  PubMed  Google Scholar 

  94. Stavrakoglou A, Dubrey SW, Dorkins H, et al. The Birt–Hogg–Dubé syndrome: dermatological features and internal malignancies. Q J Med. 2010;103:987–90.

    Article  CAS  Google Scholar 

  95. Toro J, Wei M-H, Glenn G, Weinreich M, et al. BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports. J Med Genet. 2008;45:321–31.

    Article  PubMed  CAS  Google Scholar 

  96. Gruson L. Birt-Hogg-Dube syndrome. Dermatol Online J. 2004;10(3):15–16. http://dermatology.cdlib.org Accessed 10 Nov 2008.

    Google Scholar 

  97. Bernstein M, McCusker M, Grant-Kels J. Cutaneous manifestations of cystic fibrosis. Pediatr Dermatol. 2008;25:150–7.

    Article  PubMed  Google Scholar 

  98. Zedek D, Morrell D, Graham M, et al. Acrodermatitis enteropathica-like eruption and failure to thrive as presenting signs of cystic fibrosis. J Am Acad Dermatol. 2008;58:S5–8.

    Article  PubMed  Google Scholar 

  99. Franks A, Werth V. Cutaneous aspects of cardiopulmonary disease. In: Fitzpatrick TB, Freedberg IM, Eisen AZ, Wolff K, Austen KF, editors. Dermatology in general medicine. 5th ed. New York: McGraw-Hill; 2003. p. 1625–34.

    Google Scholar 

  100. Johns M. Skin wrinkling in cystic fibrosis. Med Biol Illus. 1975;25:205–10.

    PubMed  CAS  Google Scholar 

  101. Katz K, Yan A, Turner M. Aquagenic wrinkling of the palms in patients with cystic fibrosis homozygous for the delta F508 CFTR mutation. Arch Dermatol. 2005;141:621–4.

    Article  PubMed  Google Scholar 

  102. Fradin M, Kalb R, Grossman M. Recurrent cutaneous vasculitis in cystic fibrosis. Pediatr Dermatol. 1987;4:108–11.

    Article  PubMed  CAS  Google Scholar 

  103. Garty B, Scanlin T, Goldsmith D, et al. Cutaneous manifestations of cystic fibrosis: possible role of cryoglobulins. Br J Dermatol. 1989;121:655–8.

    Article  PubMed  CAS  Google Scholar 

  104. Soter N, Mihm M, Colten H. Cutaneous necrotizing venulitis in patients with cystic fibrosis. J Pediatr Scand. 1979;95:197–201.

    CAS  Google Scholar 

  105. Schidlow D, Goldsmith D, Palmer J, et al. Arthritis in cystic fibrosis. Arch Dis Child. 1984;59:377–9.

    Article  PubMed  CAS  Google Scholar 

  106. John E, Medenis R, Rao S. Cutaneous necrotizing venulitis in patients with cystic fibrosis. J Pediatr. 1980;97:505.

    PubMed  CAS  Google Scholar 

  107. Finnegan M, Hinchcliffe J, Russel-Jones D, et al. Vasculitis complicating cystic fibrosis. Q J Med. 1989;72:609–21.

    PubMed  CAS  Google Scholar 

  108. Schidlow D, Panitch H, Saeri N, et al. Purpuric rashes in cystic fibrosis. Am J Dis Child. 1989;143:1030–2.

    PubMed  CAS  Google Scholar 

  109. Abman S, Ogle J, Harbeck R, et al. Early bacteriologic, immunologic, and clinical course of young infants with cystic fibrosis identified by neonatal screening. J Pediatr. 1991;119:211–7.

    Article  PubMed  CAS  Google Scholar 

  110. Disis M, McDonald T, Colombo J, et al. Circulating immune complexes in cystic fibrosis and their correlation to clinical parameters. Pediatr Res. 1986;20:385–90.

    Article  PubMed  CAS  Google Scholar 

  111. Hodson M, Beldon I, Batten J. Circulating immune complexes in patients with cystic fibrosis in relation to clinical features. Clin Allergy. 1985;15:363–70.

    Article  PubMed  CAS  Google Scholar 

  112. Crone J, Huber W, Eichler I, Granditsch G. Acrodermatitis ­enteropathica-like eruption as the presenting sign of cystic fibrosis-case report and review of literature. Eur J Pediatr. 2002;161:475–8.

    Article  PubMed  Google Scholar 

  113. Patrizi A, Bianchi F, Neri I, Specchia F. Acrodermatitis enteropathica-like eruption as the presenting sign of cystic fibrosis. Pediatr Dermatol. 2003;20:187–8.

    Article  PubMed  CAS  Google Scholar 

  114. Hansen R, Lemen R, Revsin B. Cystic fibrosis manifesting with acrodermatitis enteropathica-like eruption. Association with essential fatty acids and zinc deficiencies. Arch Dermatol. 1983;119:51–5.

    Article  PubMed  CAS  Google Scholar 

  115. Darmstadt G, McGuire J, Ziboh V. Malnutrition-associated rash of cystic fibrosis. Pediatr Dermatol. 2000;17:337–47.

    Article  PubMed  CAS  Google Scholar 

  116. Darmstadt GL, Schmidt CP, Wechsler DS, et al. Dermatitis as a presenting sign of cystic fibrosis [comment]. Arch Dermatol. 1992;128:1358–64.

    Article  PubMed  CAS  Google Scholar 

  117. Lovett A, Kokta V, Maari C. Diffuse dermatitis: An unexpected initial presentation of cystic fibrosis. J Am Acad Dermatol. 2008;58:S1–4.

    Article  PubMed  Google Scholar 

  118. Darmstadt GL, Schmidt CP, Wechslet DS, Tunnessen WW, Rosenstein BJ. Dermatitis as a presenting sign of cystic fibrosis. Arch Dermatol. 1992;128:1389–90.

    Article  Google Scholar 

  119. Abman S, Accurso F, Bowman C. Persistent morbidity and mortality of protein calorie malnutrition in young infants with cystic fibrosis. J Pediatr Gastroenterol Nutr. 1975;5:393–6.

    Article  Google Scholar 

  120. Muñiz A, Bartle S, Foster R. Edema, anemia, hypoproteinemia, and acrodermatitis enteropathica: an uncommon initial presentation of cystic fibrosis. Pediatr Emerg Care. 2004;20:112–4.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Dermatology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, Puerto Rico

    Jennifer Rullán, Rachelle E. Seijo-Montes & Néstor P. Sánchez

  2. Department of Obstetrics and Gynecology, San Juan City Hospital, Medical Sciences Campus, San Juan, Puerto Rico

    Annie Vaillant

Authors
  1. Jennifer Rullán
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rachelle E. Seijo-Montes
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Annie Vaillant
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Néstor P. Sánchez
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jennifer Rullán .

Editor information

Editors and Affiliations

  1. and Dermatology and chairman, Department of Dermatology, Professor of Dermatopathology, Medical Sciences Campus School of Medicine, San Juan, 00931, Puerto Rico

    Néstor P. Sánchez

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Rullán, J., Seijo-Montes, R.E., Vaillant, A., Sánchez, N.P. (2012). Cutaneous Manifestations of Pulmonary Disease. In: Sánchez, N. (eds) Atlas of Dermatology in Internal Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0688-4_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-0688-4_2

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-0687-7

  • Online ISBN: 978-1-4614-0688-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation