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The Genetics of Outer Segment Morphogenesis in Zebrafish

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Retinal Degenerative Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 723))

Abstract

Appropriate outer segment (OS) morphogenesis is necessary for normal visual function. Thirty-three zebrafish mutants with OS morphogenesis defects have been reported. We describe here the phenotypes and potential mechanisms by which these mutant loci cause OS dysmorphogenesis.

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Author information

Authors and Affiliations

  1. UCD School of Biomedical and Biomolecular Sciences, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland

    Alison L. Reynolds, Oliver E. Blacque & Breandán N. Kennedy

Authors
  1. Alison L. Reynolds
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  2. Oliver E. Blacque
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  3. Breandán N. Kennedy
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Corresponding authors

Correspondence to Alison L. Reynolds or Breandán N. Kennedy .

Editor information

Editors and Affiliations

  1. University of California, San Francisco, n/a, San Francisco, 94143, USA

    Matthew M. LaVail

  2. University of Oklahoma Health Sciences C, Oklahoma City, 73104, USA

    John D. Ash

  3. Health Science Center, Dean A. McGee Eye Inst., University of Oklahoma, Stanton L. Young Blvd. 608, OKLAHOMA CITY, 73104, Oklahoma, USA

    Robert E. Anderson

  4. Division of Ophthalmology, Cole Eye Institute at the Cleveland Clin, Euclid Ave. 9500, Cleveland, 44195, Ohio, USA

    Joe G. Hollyfield

  5. Experimental Ophthalmology, University of Zurich, ZURICH, 8091, Switzerland

    Christian Grimm

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Reynolds, A.L., Blacque, O.E., Kennedy, B.N. (2012). The Genetics of Outer Segment Morphogenesis in Zebrafish. In: LaVail, M., Ash, J., Anderson, R., Hollyfield, J., Grimm, C. (eds) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, vol 723. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0631-0_55

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