Abstract
Our previous studies have observed primo vessels in the mesentery of rats between the root of the mesentery and the colon or between the small intestine and the cecum. Some research revealed the involvement of the primo vascular system in cancer metastasis in cancer-bearing nude mice. For our future studies on the role of the primo vessels in cancer, we designed the current experiment to confirm the presence of primo vessels in the mesentery of nude mice.
Methods
With Trypan blue, phalloidin, and Hoechst staining, we estimated the morphologic characters of the primo vessels in the mesentery.
Results
Our results manifested that these structures in nude mice not only had white, Âsemitransparent, threadlike appearances, but had specific rod-shaped nuclei with linear alignments, were positive to phalloidin, and were sensitive to Trypan blue. All of these data were consistent with our previous studies.
Conclusion
We conclude that primo vessels exist of the mesentery of many Âanimals and Âsuggest that these specific structures might have specific and important functions.
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References
Yoo JS, Hossein Ayati M, Kim HB et al (2010) Characterization of the primo-vascular system in the abdominal cavity of the lung cancer mouse model and its differences from the lymphatic system. PLoS One 5(4):e9940
Yoo JS, Kim HB, Won N et al (2011) Evidence for an additional metastatic route: in-vivo Imaging of cancer cells in the primo-vascular system around tumors and organs. Mol Imaging Biol 13:471–480. doi:10.1007/s11307-010-0366-1
Lee BC, Bae KH, Jhon GJ et al (2009) Bonghan system as mesenchymal stem cell niches and pathways of macrophages in adipose tissues. J Acupunct Meridian Stud 2:79–82
Baik KY, Lee J, Lee BC et al (2005) Acupuncture meridian and the intravascular Bonghan duct. Key Eng Mater 277:125–129
Yoo JS, Kim MS, Ogay V et al (2008) In vivo visualization of Bonghan ducts inside blood vessels of mice by using an Alcian blue staining method. Indian J Exp Biol 46:336–339
Sung B (2010) Bioimaging of primo-vascular system with fluorescent nanoparticles and cryo-electron microscopy of self-assembled spermine-DNA condensates. Ph.D. dissertation, Seoul National University
Lee BC, Kim SK, Soh KS (2008) Novel anatomic structures in the brain and spinal cord of rabbit that may belong to the Bonghan system of potential acupuncture meridians. J Acupunct Meridian Stud 1:29–35
Yoo JS, Won N, Kim HB et al (2010) In vivo imaging of cancer cells with electroporation of quantum dots and multispectral imaging. J. Appl. Phys. 107, 124702, doi:10.1063/1.3447858
Yoo JS, Hossein Ayati M et al (2010) Characterization of the primo-vascular system in the abdominal cavity of thelung cancer mouse model and its differences from the lymphatic system. PLoS One 5(4):e9940
An P, Dai J, Zhendong Su et al (2010) Putative primo-vascular system in mesentery of rats. J Acupunct Meridian Stud 3(4):232–240
Acknowledgments
K. Soh thanks the Association of Korean Oriental Medicine for support.
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An, P., Su, Z., Luo, H., Soh, KS. (2012). Primo Vessels in the Mesentery of Nude Mice. In: Soh, KS., Kang, K., Harrison, D. (eds) The Primo Vascular System. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0601-3_14
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DOI: https://doi.org/10.1007/978-1-4614-0601-3_14
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