Particulated/Minced Cartilage

  • Jack Farr
  • Andreas Gomoll


Particulating or mincing articular cartilage allows the chondrocytes to escape their lacunae and migrate. The freed chondrocytes are able to multiply and form new extracellular matrix. Over time, the new chondrocyte/matrix construct matures into hyaline-like cartilage. This technique has both autograft (Cartilage Autograft Implant System (CAIS™), DePuy Mitek, Raynham MA), and allograft (DeNovo® NT, Zimmer, Warsaw, IN) applications. Early positive animal outcomes have been followed by early positive clinical outcomes. The position for these techniques in the cartilage restoration/repair algorithm is under investigation, but initially it appears to be similar to current cell therapy techniques.


Particulated cartilage Minced cartilage CAIS DeNovo NT 


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Copyright information

© Springer Science+Business Media New York  2014

Authors and Affiliations

  1. 1.Department of Orthopedic SurgeryCartilage Restoration Center of IndianaGreenwoodUSA
  2. 2.OrthoIndy and Indiana Orthopedic HospitalGreenwoodUSA
  3. 3.Department of Orthopedic SurgeryBrigham and Women’s Hospital, Harvard Medical SchoolChestnut HillUSA

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